140303

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 4028569..4029108 Replicon chromosome
Accession NZ_CP044148
Organism Escherichia coli O157 strain AR-0427

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag F4V39_RS20310 Protein ID WP_001303998.1
Coordinates 4028569..4028829 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID C3TP07
Locus tag F4V39_RS20315 Protein ID WP_000729705.1
Coordinates 4028848..4029108 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F4V39_RS20295 4026252..4026830 + 579 WP_000284050.1 D-sedoheptulose 7-phosphate isomerase -
F4V39_RS20300 4026935..4027702 + 768 WP_001301698.1 class II glutamine amidotransferase -
F4V39_RS20305 4027673..4028413 - 741 WP_001225679.1 murein L,D-transpeptidase -
F4V39_RS20310 4028569..4028829 - 261 WP_001303998.1 type II toxin-antitoxin system mRNA interferase toxin YafQ Toxin
F4V39_RS20315 4028848..4029108 - 261 WP_000729705.1 type II toxin-antitoxin system antitoxin DinJ Antitoxin
F4V39_RS20320 4029294..4030067 + 774 WP_000543891.1 C40 family peptidase -
F4V39_RS20325 4030243..4030740 + 498 Protein_3877 REP-associated tyrosine transposase RayT -
F4V39_RS20330 4030885..4032597 - 1713 Protein_3878 flagellar biosynthesis protein FlhA -
F4V39_RS20335 4032569..4033354 + 786 WP_000207556.1 putative lateral flagellar export/assembly protein LafU -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-85)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-85)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10026.71 Da        Isoelectric Point: 10.3188

>T140303 WP_001303998.1 NZ_CP044148:c4028829-4028569 [Escherichia coli O157]
MNSGQFSKDVKLAQKRHKDMNKLKYLMTLLINNTLPLPAVYKDHPLQGSWKGYRDAHVEPDWILIYKLTDKLLRFERTGT
HAALFG

Download         Length: 261 bp

>T140303 NZ_CP059084:2052816-2052913 [Pantoea ananatis]
GCAAGGCGAAAGCCTCTATTAATGCCAACTTTTAGCGCACGGCTCCTTGAGAGCCATTTCCCTGGACCGAATACAGGAAT
CGTGTTCGGTCTTTTTTT

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9377.74 Da        Isoelectric Point: 5.0758

>AT140303 WP_000729705.1 NZ_CP044148:c4029108-4028848 [Escherichia coli O157]
MAANAFVRARIDEDLKNQAADVLAGMGLTISDLVRITLTKVAREKALPFDLREPNQLTIQSIKNSEAGVDVHKAKDADDL
FDKLGV

Download         Length: 261 bp

>AT140303 NZ_CP059084:c2052913-2052816 [Pantoea ananatis]
AAAAAAAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTCAAGGAGCCGTGCGCTAAAAGTTGGCATTAA
TAGAGGCTTTCGCCTTGC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References