Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 1515819..1516358 Replicon chromosome
Accession NZ_CP044143
Organism Escherichia coli O157 strain AR-0429

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag F4V41_RS08935 Protein ID WP_001303998.1
Coordinates 1516098..1516358 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID C3TP07
Locus tag F4V41_RS08930 Protein ID WP_000729705.1
Coordinates 1515819..1516079 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F4V41_RS08910 1511573..1512358 - 786 WP_000207556.1 putative lateral flagellar export/assembly protein LafU -
F4V41_RS08915 1512330..1514042 + 1713 Protein_1482 flagellar biosynthesis protein FlhA -
F4V41_RS08920 1514187..1514684 - 498 Protein_1483 REP-associated tyrosine transposase RayT -
F4V41_RS08925 1514860..1515633 - 774 WP_000543891.1 C40 family peptidase -
F4V41_RS08930 1515819..1516079 + 261 WP_000729705.1 type II toxin-antitoxin system antitoxin DinJ Antitoxin
F4V41_RS08935 1516098..1516358 + 261 WP_001303998.1 type II toxin-antitoxin system mRNA interferase toxin YafQ Toxin
F4V41_RS08940 1516514..1517254 + 741 WP_001225679.1 murein L,D-transpeptidase -
F4V41_RS08945 1517225..1517992 - 768 WP_001301698.1 class II glutamine amidotransferase -
F4V41_RS08950 1518097..1518675 - 579 WP_000284050.1 D-sedoheptulose 7-phosphate isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-85)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-85)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10026.71 Da        Isoelectric Point: 10.3188

>T140212 WP_001303998.1 NZ_CP044143:1516098-1516358 [Escherichia coli O157]
MNSGQFSKDVKLAQKRHKDMNKLKYLMTLLINNTLPLPAVYKDHPLQGSWKGYRDAHVEPDWILIYKLTDKLLRFERTGT
HAALFG

Download         Length: 261 bp

>T140212 NZ_CP059043:c1702172-1702065 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9377.74 Da        Isoelectric Point: 5.0758

>AT140212 WP_000729705.1 NZ_CP044143:1515819-1516079 [Escherichia coli O157]
MAANAFVRARIDEDLKNQAADVLAGMGLTISDLVRITLTKVAREKALPFDLREPNQLTIQSIKNSEAGVDVHKAKDADDL
FDKLGV

Download         Length: 261 bp

>AT140212 NZ_CP059043:1702220-1702286 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References