Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2611355..2611539 Replicon chromosome
Accession NZ_CP044106
Organism Staphylococcus aureus strain FDAARGOS_660

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag FOB68_RS13150 Protein ID WP_000482647.1
Coordinates 2611355..2611462 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2611479..2611539 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FOB68_RS13125 2606717..2607190 + 474 WP_000456483.1 GyrI-like domain-containing protein -
FOB68_RS13130 2607313..2608524 - 1212 WP_001191921.1 multidrug effflux MFS transporter -
FOB68_RS13135 2608707..2609366 - 660 WP_000831298.1 membrane protein -
FOB68_RS13140 2609426..2610568 - 1143 WP_001176863.1 glycerate kinase -
FOB68_RS13145 2610836..2611222 + 387 WP_000779353.1 flippase GtxA -
FOB68_RS13150 2611355..2611462 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2611479..2611539 - 61 - - Antitoxin
FOB68_RS13155 2612110..2613873 + 1764 WP_001064822.1 ABC transporter ATP-binding protein/permease -
FOB68_RS13160 2613898..2615631 + 1734 WP_000488493.1 ABC transporter ATP-binding protein/permease -
FOB68_RS13165 2615862..2616029 + 168 WP_031845053.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T140101 WP_000482647.1 NZ_CP044106:2611355-2611462 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T140101 NZ_CP058948:c288789-288532 [Escherichia coli]
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA

Antitoxin


Download         Length: 61 bp

>AT140101 NZ_CP044106:c2611539-2611479 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References