Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | hok-sok/- |
Location | 15400..15658 | Replicon | chromosome |
Accession | NZ_CP043937 | ||
Organism | Escherichia coli strain RM14516 |
Toxin (Protein)
Gene name | hokC | Uniprot ID | S1NX00 |
Locus tag | FS841_RS00075 | Protein ID | WP_000809168.1 |
Coordinates | 15400..15552 (-) | Length | 51 a.a. |
Antitoxin (RNA)
Gene name | sokC | ||
Locus tag | - | ||
Coordinates | 15601..15658 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FS841_RS00055 | 10642..11355 | - | 714 | WP_001102367.1 | acidic protein MsyB | - |
FS841_RS00060 | 11381..11785 | - | 405 | WP_000843584.1 | DUF2541 family protein | - |
FS841_RS00065 | 12161..14077 | + | 1917 | WP_000516135.1 | molecular chaperone DnaK | - |
FS841_RS00070 | 14166..15296 | + | 1131 | WP_001118464.1 | molecular chaperone DnaJ | - |
FS841_RS00075 | 15400..15552 | - | 153 | WP_000809168.1 | type I toxin-antitoxin system toxin MokC | Toxin |
- | 15601..15658 | + | 58 | - | - | Antitoxin |
FS841_RS00080 | 16138..17304 | + | 1167 | WP_000681360.1 | Na+/H+ antiporter NhaA | - |
FS841_RS00085 | 17370..18269 | + | 900 | WP_001300855.1 | transcriptional activator NhaR | - |
FS841_RS00090 | 18307..19266 | - | 960 | WP_000871674.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 51 a.a. Molecular weight: 5501.57 Da Isoelectric Point: 7.1312
>T139508 WP_000809168.1 NZ_CP043937:c15552-15400 [Escherichia coli]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE
Download Length: 153 bp
>T139508 NZ_CP058715:82276-82554 [Escherichia coli]
ATGGAGATATTCTGGACCATGCTGGCCAGCCAGGACAGGAAGCGCATTCGTGAGTACATTGCGGAGCAGAACCTGATGGC
CGCCATTGAACTGGACGAACGGATTGGTTATTCAGCCAGCAGCTTGGCCGGGCAGCCGTATAAAGGCCGCAACGGTCGTG
TGGAAGGTACCCGGGAACTGGTTATTCACCCGCATTTTGTTCTGGTTTATGAGGTCGACAGCCAGTGGGGAAAAGTGTAT
ATCCTGCGCGTATTGCATACTGCACAGAAGTGGCCATAG
ATGGAGATATTCTGGACCATGCTGGCCAGCCAGGACAGGAAGCGCATTCGTGAGTACATTGCGGAGCAGAACCTGATGGC
CGCCATTGAACTGGACGAACGGATTGGTTATTCAGCCAGCAGCTTGGCCGGGCAGCCGTATAAAGGCCGCAACGGTCGTG
TGGAAGGTACCCGGGAACTGGTTATTCACCCGCATTTTGTTCTGGTTTATGAGGTCGACAGCCAGTGGGGAAAAGTGTAT
ATCCTGCGCGTATTGCATACTGCACAGAAGTGGCCATAG
Antitoxin
Download Length: 58 bp
>AT139508 NZ_CP043937:15601-15658 [Escherichia coli]
GTTCAGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA
GTTCAGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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