Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 3490895..3491595 Replicon chromosome
Accession NZ_CP043929
Organism Methylomonas rhizoryzae strain GJ1

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag F1E05_RS15640 Protein ID WP_150050078.1
Coordinates 3490895..3491191 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag F1E05_RS15645 Protein ID WP_150050080.1
Coordinates 3491194..3491595 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F1E05_RS15595 3486346..3486576 + 231 WP_150050050.1 hypothetical protein -
F1E05_RS15600 3486578..3487111 + 534 WP_150050052.1 hypothetical protein -
F1E05_RS15605 3487265..3487645 + 381 WP_150050054.1 hypothetical protein -
F1E05_RS15610 3487845..3488240 + 396 WP_150050056.1 hypothetical protein -
F1E05_RS15615 3488237..3488458 + 222 WP_150050058.1 hypothetical protein -
F1E05_RS15620 3488455..3488637 + 183 WP_150050060.1 hypothetical protein -
F1E05_RS15625 3488775..3489125 - 351 WP_150050062.1 retroviral-like aspartic protease family protein -
F1E05_RS15630 3489103..3489855 - 753 WP_150050064.1 hypothetical protein -
F1E05_RS15635 3490183..3490851 + 669 WP_150050066.1 KilA-N domain-containing protein -
F1E05_RS15640 3490895..3491191 + 297 WP_150050078.1 type II toxin-antitoxin system MqsR family toxin Toxin
F1E05_RS15645 3491194..3491595 + 402 WP_150050080.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
F1E05_RS15650 3491941..3492558 - 618 WP_150050082.1 hypothetical protein -
F1E05_RS15655 3492652..3493458 - 807 WP_150050084.1 hypothetical protein -
F1E05_RS15660 3493506..3496064 - 2559 WP_190303167.1 death domain-containing protein -
F1E05_RS15665 3496279..3496482 - 204 WP_150050086.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(2-97)

Antitoxin

Antitoxin MqsA/HigA-2

(1-131)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10871.65 Da        Isoelectric Point: 8.0409

>T139476 WP_150050078.1 NZ_CP043929:3490895-3491191 [Methylomonas rhizoryzae]
MEKQTPHCKLPAIKALVANGKVRTTKSAREGATALGFDYDGMLVVIMSLTPADFYKSMTTHADHKVWQDVYRPNTVAGDV
YLKLTVIDDVLVVSFKEL

Download         Length: 297 bp

>T139476 NZ_CP058709:c2226328-2226041 [Escherichia coli]
ATGCCAATGGAGTTTGAATGGGATGAAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTGAAGATGCGGT
GTTATTGTTTGATGATCCACAACATTTGTCACAGCAAGAACGCATAGAAAACGGTGAGTATCGCTGGCAGACAATCGGCC
TGGTTTACGGCATCGTGGTTATTCTGGTTGCGCATACCATCCGTTTCGAAAGCGGAAATGAAATTATTCGAATCATCAGT
GCACGAAAAGCAGATCGTAAAGAGAGGAATCGCTATGAGCATGGTTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14612.78 Da        Isoelectric Point: 4.9837

>AT139476 WP_150050080.1 NZ_CP043929:3491194-3491595 [Methylomonas rhizoryzae]
MKCPSCGAVELVKDTRDLSYTYKGESTTIPDVTGEFCPACDEVITDADESRRTMALMMEFNKQVNASIVDPGFIASVRKK
LALDQREAGELFGGGINAFSRYETGKTKPPLALVKLLKVLDRHPDLLDEIRAA

Download         Length: 402 bp

>AT139476 NZ_CP058709:c2226054-2225752 [Escherichia coli]
ATGAGCATGGTTAAACATAAACGAGGGACCTCCTCTACACTCGATGTGCAGCATGAGGCCGAACTGAAGGCGCTGACGAA
TAAATCCGACGAAGATATTGATTACAGTGATATCCCACCTTCCAGCGATGAGCAATGGTCTAACGCCGAACGCGGTAAGT
TTTATCGGCCATTGAAAACTCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGTTGAAGCGACCAGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References