Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/YoeB-RelB |
Location | 2865997..2866506 | Replicon | chromosome |
Accession | NZ_CP043633 | ||
Organism | Nonlabens sp. Ci31 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | - |
Locus tag | F0365_RS12580 | Protein ID | WP_169934012.1 |
Coordinates | 2866246..2866506 (+) | Length | 87 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | - |
Locus tag | F0365_RS12575 | Protein ID | WP_169934011.1 |
Coordinates | 2865997..2866245 (+) | Length | 83 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
F0365_RS12555 | 2861368..2861790 | + | 423 | WP_169934007.1 | hypothetical protein | - |
F0365_RS12560 | 2862120..2863349 | + | 1230 | WP_169934008.1 | RHS repeat-associated core domain-containing protein | - |
F0365_RS12565 | 2863312..2863854 | + | 543 | WP_169934009.1 | hypothetical protein | - |
F0365_RS12570 | 2864524..2865051 | + | 528 | WP_169934010.1 | ORF6N domain-containing protein | - |
F0365_RS12575 | 2865997..2866245 | + | 249 | WP_169934011.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
F0365_RS12580 | 2866246..2866506 | + | 261 | WP_169934012.1 | Txe/YoeB family addiction module toxin | Toxin |
F0365_RS12585 | 2867165..2867692 | + | 528 | WP_169934013.1 | hypothetical protein | - |
F0365_RS12590 | 2867969..2868517 | + | 549 | WP_169934014.1 | transposase | - |
F0365_RS12595 | 2868521..2868733 | + | 213 | WP_169934015.1 | hypothetical protein | - |
F0365_RS12600 | 2868733..2869158 | + | 426 | WP_169934016.1 | hypothetical protein | - |
F0365_RS12605 | 2869635..2869904 | + | 270 | WP_169934017.1 | hypothetical protein | - |
F0365_RS12610 | 2870140..2870667 | + | 528 | WP_169934018.1 | ORF6N domain-containing protein | - |
F0365_RS12615 | 2871132..2871296 | + | 165 | WP_169934019.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 87 a.a. Molecular weight: 10300.98 Da Isoelectric Point: 9.7572
>T139169 WP_169934012.1 NZ_CP043633:2866246-2866506 [Nonlabens sp. Ci31]
MKLTWSTSSWEDYLYWQKVDKKIVKRINELIKSCLRTPFEGIGKPEALKGDLQGYLSRRITSEHRLVYKYEKEEILIAAC
RYHYGK
MKLTWSTSSWEDYLYWQKVDKKIVKRINELIKSCLRTPFEGIGKPEALKGDLQGYLSRRITSEHRLVYKYEKEEILIAAC
RYHYGK
Download Length: 261 bp
>T139169 NZ_CP058544:c5269621-5269088 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCTGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCTGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9415.81 Da Isoelectric Point: 7.0107
>AT139169 WP_169934011.1 NZ_CP043633:2865997-2866245 [Nonlabens sp. Ci31]
METVNYTDFRSNLKHWFDKVVNDVSDIIIKRKSGKDLVLISLDEYNSLKETTYLLTGKNRDILLNSIKELEAGKGVQKGL
IE
METVNYTDFRSNLKHWFDKVVNDVSDIIIKRKSGKDLVLISLDEYNSLKETTYLLTGKNRDILLNSIKELEAGKGVQKGL
IE
Download Length: 249 bp
>AT139169 NZ_CP058544:c5269898-5269632 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
GGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
GGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|
Antitoxin
Source | ID | Structure |
---|