Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2865997..2866506 Replicon chromosome
Accession NZ_CP043633
Organism Nonlabens sp. Ci31

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag F0365_RS12580 Protein ID WP_169934012.1
Coordinates 2866246..2866506 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag F0365_RS12575 Protein ID WP_169934011.1
Coordinates 2865997..2866245 (+) Length 83 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F0365_RS12555 2861368..2861790 + 423 WP_169934007.1 hypothetical protein -
F0365_RS12560 2862120..2863349 + 1230 WP_169934008.1 RHS repeat-associated core domain-containing protein -
F0365_RS12565 2863312..2863854 + 543 WP_169934009.1 hypothetical protein -
F0365_RS12570 2864524..2865051 + 528 WP_169934010.1 ORF6N domain-containing protein -
F0365_RS12575 2865997..2866245 + 249 WP_169934011.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
F0365_RS12580 2866246..2866506 + 261 WP_169934012.1 Txe/YoeB family addiction module toxin Toxin
F0365_RS12585 2867165..2867692 + 528 WP_169934013.1 hypothetical protein -
F0365_RS12590 2867969..2868517 + 549 WP_169934014.1 transposase -
F0365_RS12595 2868521..2868733 + 213 WP_169934015.1 hypothetical protein -
F0365_RS12600 2868733..2869158 + 426 WP_169934016.1 hypothetical protein -
F0365_RS12605 2869635..2869904 + 270 WP_169934017.1 hypothetical protein -
F0365_RS12610 2870140..2870667 + 528 WP_169934018.1 ORF6N domain-containing protein -
F0365_RS12615 2871132..2871296 + 165 WP_169934019.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-84)

Antitoxin

(1-72)


Sequences


Toxin        


Download         Length: 87 a.a.        Molecular weight: 10300.98 Da        Isoelectric Point: 9.7572

>T139169 WP_169934012.1 NZ_CP043633:2866246-2866506 [Nonlabens sp. Ci31]
MKLTWSTSSWEDYLYWQKVDKKIVKRINELIKSCLRTPFEGIGKPEALKGDLQGYLSRRITSEHRLVYKYEKEEILIAAC
RYHYGK

Download         Length: 261 bp

>T139169 NZ_CP058544:c5269621-5269088 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCTGGG
CTGGGGAGAGATGTTGGTTGCCCATGCGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAGGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9415.81 Da        Isoelectric Point: 7.0107

>AT139169 WP_169934011.1 NZ_CP043633:2865997-2866245 [Nonlabens sp. Ci31]
METVNYTDFRSNLKHWFDKVVNDVSDIIIKRKSGKDLVLISLDEYNSLKETTYLLTGKNRDILLNSIKELEAGKGVQKGL
IE

Download         Length: 249 bp

>AT139169 NZ_CP058544:c5269898-5269632 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
GGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References