Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 5248263..5248969 Replicon chromosome
Accession NZ_CP043626
Organism Pseudomonas denitrificans (nom. rej.) strain BG1

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag F1C79_RS24245 Protein ID WP_151188805.1
Coordinates 5248263..5248562 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag F1C79_RS24250 Protein ID WP_151188806.1
Coordinates 5248565..5248969 (+) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F1C79_RS24225 5243938..5245044 + 1107 WP_024766695.1 GlxA family transcriptional regulator -
F1C79_RS24230 5245210..5246673 + 1464 WP_151188803.1 hypothetical protein -
F1C79_RS24235 5246736..5247203 - 468 WP_151189762.1 phage antirepressor -
F1C79_RS24240 5247756..5248154 - 399 WP_151188804.1 VOC family protein -
F1C79_RS24245 5248263..5248562 + 300 WP_151188805.1 type II toxin-antitoxin system MqsR family toxin Toxin
F1C79_RS24250 5248565..5248969 + 405 WP_151188806.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
F1C79_RS24255 5249131..5249514 - 384 WP_151188807.1 hypothetical protein -
F1C79_RS24260 5249691..5250059 - 369 Protein_4778 hypothetical protein -
F1C79_RS24265 5251236..5251601 - 366 WP_151188808.1 hypothetical protein -
F1C79_RS24270 5251743..5252204 - 462 WP_151188809.1 SMI1/KNR4 family protein -
F1C79_RS24275 5252499..5252813 - 315 WP_151188810.1 hypothetical protein -
F1C79_RS32115 5252815..5253126 - 312 WP_167523301.1 adhesin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(3-98)

Antitoxin

Antitoxin MqsA/HigA-2

(1-132)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11407.21 Da        Isoelectric Point: 9.9870

>T139159 WP_151188805.1 NZ_CP043626:5248263-5248562 [Pseudomonas denitrificans (nom. rej.)]
MDKRTPHHKLPLIRLAIAERRYRFTRVALEGALELGLESTEQVLAVITGLTSADFYKSMTTYADHSIWQDVYRPRVNGRQ
AYVKLTLQGDLLIVSFKEK

Download         Length: 300 bp

>T139159 NZ_CP058544:c561500-561117 [Klebsiella pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 14986.02 Da        Isoelectric Point: 5.9914

>AT139159 WP_151188806.1 NZ_CP043626:5248565-5248969 [Pseudomonas denitrificans (nom. rej.)]
MLCPVCGQADLVHAIRDLPYTYKGQFTTIPQVEADWCDACGESITGPTESERVMQAMAEHRRQVNQAAGHQTLIREVRKE
LLHLSQREAGELFGGGPNAFSRYERGETEPPVALVKLFGILKTHPELAKEVRQE

Download         Length: 405 bp

>AT139159 NZ_CP058544:c561742-561500 [Klebsiella pneumoniae]
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATACCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCATGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References