Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 909333..909921 Replicon chromosome
Accession NZ_CP043617
Organism Sulfurimonas sp. GYSZ_1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag FJR48_RS04590 Protein ID WP_152306984.1
Coordinates 909333..909617 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag FJR48_RS04595 Protein ID WP_152306985.1
Coordinates 909628..909921 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FJR48_RS04575 906103..908052 + 1950 WP_152306981.1 NAD-dependent DNA ligase LigA -
FJR48_RS04580 908049..908582 + 534 WP_152306982.1 outer membrane beta-barrel protein -
FJR48_RS04585 908582..909289 + 708 WP_152306983.1 TlyA family RNA methyltransferase -
FJR48_RS04590 909333..909617 + 285 WP_152306984.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FJR48_RS04595 909628..909921 + 294 WP_152306985.1 HigA family addiction module antidote protein Antitoxin
FJR48_RS04600 909943..910767 + 825 WP_152306986.1 bifunctional riboflavin kinase/FAD synthetase -
FJR48_RS04605 910764..911783 + 1020 WP_152306987.1 tRNA pseudouridine(13) synthase TruD -
FJR48_RS04615 912057..912581 + 525 WP_188108628.1 transglycosylase SLT domain-containing protein -
FJR48_RS04620 912650..914398 + 1749 WP_152306989.1 DUF3365 domain-containing protein -
FJR48_RS04625 914432..914893 - 462 WP_152306990.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(3-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-69)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11166.77 Da        Isoelectric Point: 9.7834

>T139153 WP_152306984.1 NZ_CP043617:909333-909617 [Sulfurimonas sp. GYSZ_1]
MIKSFKCKYTKKLFDGKSQKKFSQAVNNVGKRKLDMLEASYDEADLRVPPSNRFEHLKGDLKGFCSIRINEQYRIVFRFE
NSNAYDVYIDDYHK

Download         Length: 285 bp

>T139153 NZ_CP058527:c400189-399770 [Agrobacterium tumefaciens]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11101.77 Da        Isoelectric Point: 7.2741

>AT139153 WP_152306985.1 NZ_CP043617:909628-909921 [Sulfurimonas sp. GYSZ_1]
MLDIRPSTHPGVILREEFATPLNLTQAKLSEDLNVGIKTLSELYNEKRGITSLMALKLAEYFGTTPHFWMNLQNAYDLYK
TYEKEKNNIKNIAHCAA

Download         Length: 294 bp

>AT139153 NZ_CP058527:c400440-400186 [Agrobacterium tumefaciens]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References