139051

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 4084682..4085270 Replicon chromosome
Accession NZ_CP043578
Organism Stenotrophomonas maltophilia strain T50-20

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag F0Q13_RS18755 Protein ID WP_080356578.1
Coordinates 4084992..4085270 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag F0Q13_RS18750 Protein ID WP_049463234.1
Coordinates 4084682..4084981 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F0Q13_RS18730 4080095..4081282 + 1188 WP_182266723.1 pyridoxal phosphate-dependent aminotransferase -
F0Q13_RS18735 4081419..4083515 - 2097 WP_049463220.1 prolyl oligopeptidase family protein -
F0Q13_RS18740 4083585..4083911 - 327 WP_110713762.1 hypothetical protein -
F0Q13_RS18745 4084039..4084641 + 603 WP_182266724.1 lipocalin family protein -
F0Q13_RS18750 4084682..4084981 - 300 WP_049463234.1 HigA family addiction module antidote protein Antitoxin
F0Q13_RS18755 4084992..4085270 - 279 WP_080356578.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
F0Q13_RS18760 4085526..4086215 - 690 WP_032129021.1 ABC transporter permease -
F0Q13_RS18765 4086212..4087219 - 1008 WP_032129022.1 methionine ABC transporter ATP-binding protein -
F0Q13_RS18770 4087420..4088316 - 897 WP_182266725.1 DMT family transporter -
F0Q13_RS18775 4088594..4089076 + 483 WP_006471121.1 YajQ family cyclic di-GMP-binding protein -
F0Q13_RS18780 4089112..4090209 - 1098 WP_049399220.1 Fis family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(1-92)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(8-83)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10686.18 Da        Isoelectric Point: 9.9466

>T139051 WP_080356578.1 NZ_CP043578:c4085270-4084992 [Stenotrophomonas maltophilia]
MIRSFRCKQTRALFEGTCPRAWLSIRRAAERKLQLLDSAQTLAFLRSPPGNRLEALSGDRRGQYSLRINDQWRLCFTWTD
NGADAVEIVDYH

Download         Length: 279 bp

>T139051 NZ_CP058342:c4306221-4306048 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10916.62 Da        Isoelectric Point: 11.2297

>AT139051 WP_049463234.1 NZ_CP043578:c4084981-4084682 [Stenotrophomonas maltophilia]
MKRPHNGMRAIHPGEILREEFLMPLALSVNALARALDVPATRLHAIVHGERSISADTAARLARHFGGDAASWLAMQAAYD
LKTLPTRSEIERRVQPRAA

Download         Length: 300 bp

>AT139051 NZ_CP043578:c4084981-4084682 [Stenotrophomonas maltophilia]
ATGAAGCGTCCCCACAACGGCATGCGCGCCATCCATCCTGGCGAGATCCTGCGCGAAGAGTTCCTGATGCCTCTGGCGTT
GAGCGTGAACGCGCTGGCAAGGGCCTTGGATGTTCCCGCAACACGGCTGCACGCCATCGTGCACGGGGAGCGCAGTATTT
CGGCCGATACCGCGGCACGGCTGGCGCGACATTTTGGTGGGGATGCCGCGTCCTGGCTTGCGATGCAGGCGGCCTACGAC
CTCAAGACATTGCCAACGCGCAGCGAGATCGAGCGACGGGTACAGCCGCGGGCTGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References