Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 39406..39947 Replicon plasmid unnamed1
Accession NZ_CP043507
Organism Acetobacter sp. KACC 21233

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag FLP30_RS12840 Protein ID WP_149280422.1
Coordinates 39678..39947 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag FLP30_RS12835 Protein ID WP_149280421.1
Coordinates 39406..39681 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FLP30_RS12815 34566..34937 + 372 WP_149280418.1 hypothetical protein -
FLP30_RS12820 34997..36240 + 1244 Protein_35 IS701 family transposase -
FLP30_RS12825 36364..37158 - 795 WP_149280419.1 EAL domain-containing protein -
FLP30_RS12830 37388..38797 - 1410 WP_149280420.1 methyl-accepting chemotaxis protein -
FLP30_RS12835 39406..39681 + 276 WP_149280421.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FLP30_RS12840 39678..39947 + 270 WP_149280422.1 Txe/YoeB family addiction module toxin Toxin
FLP30_RS12845 40267..40581 - 315 WP_149280423.1 hypothetical protein -
FLP30_RS12850 40614..43793 - 3180 WP_149280424.1 relaxase domain-containing protein -
FLP30_RS12855 43790..44059 - 270 WP_149280425.1 hypothetical protein -
FLP30_RS12860 44143..44514 - 372 WP_149280426.1 type II toxin-antitoxin system death-on-curing family toxin -
FLP30_RS12865 44511..44741 - 231 WP_149280427.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..165009 165009


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10665.07 Da        Isoelectric Point: 8.1012

>T138904 WP_149280422.1 NZ_CP043507:39678-39947 [Acetobacter sp. KACC 21233]
VKVFFHENGWEDYLSWFQSDTALLGKINTLIEDVRRHPFQGLGKPEPLKGQLTGWWSRRITGEHRLVYRVRGHAEDDQRI
EVIQCRFHY

Download         Length: 270 bp

>T138904 NZ_CP058278:3409008-3409301 [Flavobacterium sp. P2-65]
ATGGCTAAATTTTACTTGACCAATAAAGCTGTAGAAGACTTGGGTGACATTTGGAATTACACCGTAGAAGCATGGTCAGA
AAATCAAGCAGAAATTTATTATTCCTTAATTATAGATTCCTTTCAGGAATTAGCGAGTAAGCCAAATCAAGGAAAATCAT
ATGATGTAGTAGAAAGAAATGTTTTAGGTTATAAAACCGGACAACATGTAATTTTTTACAGAATTGTGACAGAAAGAGAA
ATCGAAGTTATTAGAATTTCACACGGTATGATGGACATGAAAAACCACCTATAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10247.52 Da        Isoelectric Point: 4.4475

>AT138904 WP_149280421.1 NZ_CP043507:39406-39681 [Acetobacter sp. KACC 21233]
MTCVSYTDLRQNLAYYLDEAVNSRAPIIVTRKTGKGAVVLMSEEEFSGWQETVHLLSSPHNAERLLQSIRDMECGAMTEQ
DILEPRDTQSA

Download         Length: 276 bp

>AT138904 NZ_CP058278:3408767-3409015 [Flavobacterium sp. P2-65]
ATGGGACGAAACACATCTATATCATTAGGTCCTCATTTCGAAAGTTTTATTGAATCAACTGTTTCGAAAGGGCGCTTTAG
CAACGCAAGTGAAGTTGTTAGAGCCGGACTTAGGCTATTAGAAGAAGAAGAAAACAGAATTACTGTTTTAAGAAATGCCA
TTCAAGAAGGAATTGAAAGTGGACGCGCCGAAAACTTTGATCCTAAAAAGCATCTGGAAACTTTAAAGTCAAAAAAGAAG
AATGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References