Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/YoeB-YefM |
Location | 2167474..2167976 | Replicon | chromosome |
Accession | NZ_CP043487 | ||
Organism | Escherichia coli strain AQ15 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | U9YDH0 |
Locus tag | FQT78_RS10560 | Protein ID | WP_000767829.1 |
Coordinates | 2167474..2167728 (-) | Length | 85 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | S1Q063 |
Locus tag | FQT78_RS10565 | Protein ID | WP_001259255.1 |
Coordinates | 2167725..2167976 (-) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FQT78_RS10530 | 2162489..2162716 | - | 228 | WP_000985273.1 | sulfurtransferase TusA family protein | - |
FQT78_RS10535 | 2162730..2163788 | - | 1059 | WP_000492346.1 | transport protein YeeE | - |
FQT78_RS10540 | 2163967..2165325 | - | 1359 | WP_000019197.1 | putrescine/proton symporter PlaP | - |
FQT78_RS10545 | 2165315..2165377 | - | 63 | WP_010723108.1 | membrane protein YoeI | - |
FQT78_RS10550 | 2165592..2166521 | - | 930 | WP_000803351.1 | LysR family transcriptional regulator | - |
FQT78_RS10555 | 2166567..2167391 | - | 825 | WP_000754749.1 | SDR family oxidoreductase | - |
FQT78_RS10560 | 2167474..2167728 | - | 255 | WP_000767829.1 | type II toxin-antitoxin system mRNA interferase toxin YoeB | Toxin |
FQT78_RS10565 | 2167725..2167976 | - | 252 | WP_001259255.1 | YoeB-YefM toxin-antitoxin system antitoxin YefM | Antitoxin |
FQT78_RS10570 | 2168259..2168309 | + | 51 | WP_001364200.1 | his operon leader peptide | - |
FQT78_RS10575 | 2168455..2169354 | + | 900 | WP_000131782.1 | ATP phosphoribosyltransferase | - |
FQT78_RS10580 | 2169360..2170664 | + | 1305 | WP_001349967.1 | histidinol dehydrogenase | - |
FQT78_RS10585 | 2170661..2171731 | + | 1071 | WP_000108957.1 | histidinol-phosphate transaminase | - |
FQT78_RS10590 | 2171731..2172798 | + | 1068 | WP_000080093.1 | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 10183.58 Da Isoelectric Point: 8.0353
>T138877 WP_000767829.1 NZ_CP043487:c2167728-2167474 [Escherichia coli]
VKLIWSEESWDDYLYWQETDKRIVKKINELIKDTRRTPFEGKGKPEPLKHNLSGFWSRRITEEHRLVYAVTDDSLLIAAC
RYHY
VKLIWSEESWDDYLYWQETDKRIVKKINELIKDTRRTPFEGKGKPEPLKHNLSGFWSRRITEEHRLVYAVTDDSLLIAAC
RYHY
Download Length: 255 bp
>T138877 NZ_CP058242:c2219769-2219518 [Bacillus subtilis]
ATGAACTTCTCCTTTAGTTCCTACCCATATTATAACATGATCAAGCACATTGCAAACATGAAACGATTCTCATTATGGTT
TACCCATATCACATTCATTGGCTTATTCTTAATGTTTCAACTCATCAAAGATTACTTCAGCAGCGAAGGACAGGCGCTAA
TCAACACAATTTTTGTTGTCACATGTATCATTGCCATATTGTTATGGATCATCTATTGTGTATTCCTTAAACTAAGAAAC
AAGTCACACTAA
ATGAACTTCTCCTTTAGTTCCTACCCATATTATAACATGATCAAGCACATTGCAAACATGAAACGATTCTCATTATGGTT
TACCCATATCACATTCATTGGCTTATTCTTAATGTTTCAACTCATCAAAGATTACTTCAGCAGCGAAGGACAGGCGCTAA
TCAACACAATTTTTGTTGTCACATGTATCATTGCCATATTGTTATGGATCATCTATTGTGTATTCCTTAAACTAAGAAAC
AAGTCACACTAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9307.58 Da Isoelectric Point: 4.7954
>AT138877 WP_001259255.1 NZ_CP043487:c2167976-2167725 [Escherichia coli]
MRTISYSEARQNLSATMMKAVEDHAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANARRLMDSIDSLKSGKGTEKD
IIE
MRTISYSEARQNLSATMMKAVEDHAPILITRQNGEACVLMSLEEYNSLEETAYLLRSPANARRLMDSIDSLKSGKGTEKD
IIE
Download Length: 252 bp
>AT138877 NZ_CP058242:2219747-2219847 [Bacillus subtilis]
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT
TAGGAACTAAAGGAGAAGTTCATTCCCCTTTAGCTTAGCTCTCATCGGCGTATACGTTGGCGTTGTCTCTTTGGTCGGAG
CCGCTTGCGTATACGCTTTTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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