Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 2786189..2787642 Replicon chromosome
Accession NZ_CP043403
Organism Xanthomonas oryzae pv. oryzicola strain GX01

Toxin (Protein)


Gene name rlegT Uniprot ID A0A5C2EYQ5
Locus tag XOCgx_RS13150 Protein ID WP_047339759.1
Coordinates 2786189..2787040 (-) Length 284 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A0C5V250
Locus tag XOCgx_RS13155 Protein ID WP_024710981.1
Coordinates 2787037..2787642 (-) Length 202 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XOCgx_RS13120 2781229..2782191 - 963 WP_044751530.1 IS110 family transposase -
XOCgx_RS23180 2782416..2782718 - 303 WP_047339762.1 hypothetical protein -
XOCgx_RS13135 2783591..2783932 - 342 WP_050585837.1 ParB N-terminal domain-containing protein -
XOCgx_RS13140 2783929..2785495 - 1567 Protein_2373 recombinase family protein -
XOCgx_RS13145 2785632..2786102 - 471 WP_149621647.1 hypothetical protein -
XOCgx_RS13150 2786189..2787040 - 852 WP_047339759.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
XOCgx_RS13155 2787037..2787642 - 606 WP_024710981.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
XOCgx_RS13160 2787886..2788233 - 348 WP_149621648.1 hypothetical protein -
XOCgx_RS13165 2788184..2788696 - 513 WP_161600049.1 helix-turn-helix domain-containing protein -
XOCgx_RS23450 2788997..2789173 + 177 WP_014503024.1 hypothetical protein -
XOCgx_RS13170 2789485..2790570 + 1086 WP_048485514.1 sensor domain-containing diguanylate cyclase -
XOCgx_RS13175 2790613..2791122 - 510 WP_014503022.1 chemotaxis protein CheW -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2768187..2795933 27746
flank IS/Tn - - 2781229..2782191 962


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(34-262)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(8-55)


Sequences

Toxin        


Download         Length: 284 a.a.        Molecular weight: 31056.91 Da        Isoelectric Point: 7.0657

>T138661 WP_047339759.1 NZ_CP043403:c2787040-2786189 [Xanthomonas oryzae pv. oryzicola]
MSNVAASVRARLRGVAKAQGVDFNQVLVRFALERILYRLSQSEHADRFLLKGALLFTLWYDMPHRATRDADLLGFGASDL
ESVAQTFRDIASVAVDDGIVFDPASVVAEEIRKDAGYAGARILIGGELAKARCRTQIDVGFGDAVTPAPVHSVYPVLLED
LPAPRLRTYPVYTVIAEKLHAIALLGMTNSRMKDYLDLSVLLERESLDIDLLAQAVKATFERRGMAVPAALPIGMTDEFA
HDTSRQALWQAFLKKNELAPEPLAAIVVRLRAALEPALHRAAR

Download         Length: 852 bp

>T138661 NZ_CP058193:c1378-1070 [Enterobacter hormaechei]
ATGCAGTTCACGGTTTACCGCAATAATGGCAATAGTCGGGCTTATCCTTACCTGCTGGACGTGCAGAGCGATATTATCGG
CGAACTCAAAACGCGACTGGTGATTCCCCTGTATTCGCTGAATGAGTTCAGTGGACGGCCTGCTCGTCGTCTTAATCCAG
TGCTGAATGTGGAGGATGAGGATTATCTGGTCATGACTCATGAAATGGCAAGCGTAAGGCTGTCACAACTGGGGGATGAG
GTGGTAAGCGTTCGGGAACACCGCGAGGTCATCAAGAACGCTCTGGATTTTCTGCTGGATGGGTTCTGA

Antitoxin


Download         Length: 202 a.a.        Molecular weight: 22257.92 Da        Isoelectric Point: 9.9253

>AT138661 WP_024710981.1 NZ_CP043403:c2787642-2787037 [Xanthomonas oryzae pv. oryzicola]
MLSDTHTQRVLDLASQKGLLRASDLDAINAPRVVLTRLTAAGVLERVGRGLYRLPDAQGSEFESLAAIATKVPQAVFCLL
TALQFHELTTQLPRQIWIAMPRGSHAPRIGYPPVKMVQMTGDVYAAGIEEHLRDGVRLRVYGAAKTVVDCFKHRNKIGLD
VALEALKDVRAKRKATADDLWRFATVCRVANVMRPYLEAVE

Download         Length: 606 bp

>AT138661 NZ_CP058193:c1620-1381 [Enterobacter hormaechei]
ATGACAACATCAGTCATGCGCCATAAAAAAACCGTCAGTGTGACACTCGAGCCAGCCCTTTTGCGTCAGGCACGCGAAGC
GGGGATCAATCTGTCTGCTACATTGGCCACTGCCCTGAGACACGAGATACGCGAGTCTGAATCTGAGCGCTGGAAGCGTA
CCAATCGTAAGGCAATTCAGGAATTGAACCGTATTACGGACGAACACGGCTTACTCTCTGACGATTACAGGACGTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5C2EYQ5

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V250

References