Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | sprG-sprF/- |
Location | 2271096..2271313 | Replicon | chromosome |
Accession | NZ_CP043392 | ||
Organism | Staphylococcus aureus strain NRS384-rpoB-H481N-NCV |
Toxin (Protein)
Gene name | SprG3 | Uniprot ID | Q2FWA7 |
Locus tag | FZC50_RS11685 | Protein ID | WP_001802298.1 |
Coordinates | 2271209..2271313 (-) | Length | 35 a.a. |
Antitoxin (RNA)
Gene name | SprF4 | ||
Locus tag | - | ||
Coordinates | 2271096..2271151 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FZC50_RS11665 | 2267233..2267898 | - | 666 | WP_001024094.1 | SDR family oxidoreductase | - |
FZC50_RS11670 | 2268050..2268370 | + | 321 | WP_000003759.1 | Zn(II)-responsive metalloregulatory transcriptional repressor CzrA | - |
FZC50_RS11675 | 2268372..2269352 | + | 981 | WP_000019744.1 | CDF family zinc efflux transporter CzrB | - |
FZC50_RS11680 | 2269618..2270709 | + | 1092 | WP_000495671.1 | lytic regulatory protein | - |
- | 2271096..2271151 | + | 56 | - | - | Antitoxin |
FZC50_RS11685 | 2271209..2271313 | - | 105 | WP_001802298.1 | hypothetical protein | Toxin |
FZC50_RS11690 | 2271474..2271957 | - | 484 | Protein_2206 | recombinase family protein | - |
FZC50_RS11695 | 2272000..2273136 | - | 1137 | WP_000115564.1 | SAP domain-containing protein | - |
FZC50_RS11700 | 2273425..2273517 | + | 93 | WP_001790138.1 | hypothetical protein | - |
FZC50_RS11705 | 2274222..2275079 | - | 858 | WP_000370924.1 | Cof-type HAD-IIB family hydrolase | - |
FZC50_RS11710 | 2275147..2275929 | - | 783 | WP_000908176.1 | ABC transporter ATP-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 35 a.a. Molecular weight: 3906.77 Da Isoelectric Point: 5.5724
>T138615 WP_001802298.1 NZ_CP043392:c2271313-2271209 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
Download Length: 105 bp
>T138615 NZ_CP058168:57856-58161 [Enterobacter hormaechei]
ATGCAGTTTAAGGTTTATGCCTATAAAAGAGAGAGTCGCTATCGTCTGTTCGTGGATGTGCAGAGTGACATCATCGATAC
CCCCGGGCGGCGCATGGTGATCCCGCTGGCCAGCGCCCGGCTGCTGTCGGATAAGGTCTCCCGTGATCTCTATCCGGTGG
TGCACATCGGGGACGACAGCTATCGCCTGATGACCACGGACATGGCCAGCGTCACGGCCTCTGTCACCGGGGAGGAAGTG
GCCGATCTCAGCCACCGGGAAAATGACATCAAAAATGCGATAAACCTGATGTTCTGGGGAATTTGA
ATGCAGTTTAAGGTTTATGCCTATAAAAGAGAGAGTCGCTATCGTCTGTTCGTGGATGTGCAGAGTGACATCATCGATAC
CCCCGGGCGGCGCATGGTGATCCCGCTGGCCAGCGCCCGGCTGCTGTCGGATAAGGTCTCCCGTGATCTCTATCCGGTGG
TGCACATCGGGGACGACAGCTATCGCCTGATGACCACGGACATGGCCAGCGTCACGGCCTCTGTCACCGGGGAGGAAGTG
GCCGATCTCAGCCACCGGGAAAATGACATCAAAAATGCGATAAACCTGATGTTCTGGGGAATTTGA
Antitoxin
Download Length: 56 bp
>AT138615 NZ_CP043392:2271096-2271151 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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