Detailed information of TA system TA138588

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 466810..466992
• Replicon: chromosome
• Accession: NZ_CP043389
• Organism: Staphylococcus aureus strain NRS384-rpoB-H481N-SCV

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: FZC51_RS02230
• Protein ID: WP_001801861.1
• Coordinates: 466897..466992 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	466810..466869 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FZC51_RS02215	465948..466325	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
FZC51_RS02220	466519..466695	+	177	Protein_428	transposase	-
FZC51_RS02225	466673..466774	-	102	WP_001791893.1	hypothetical protein	-
-	466810..466869	+	60	-	-	Antitoxin
FZC51_RS02230	466897..466992	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
FZC51_RS02240	467195..467338	+	144	WP_001549059.1	transposase	-
FZC51_RS02250	467942..468325	+	384	WP_000070811.1	hypothetical protein	-
FZC51_RS02255	468336..468512	+	177	WP_000375476.1	hypothetical protein	-
FZC51_RS02260	468514..468699	+	186	WP_000809857.1	hypothetical protein	-
FZC51_RS02265	468813..469454	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
FZC51_RS02270	469672..470223	-	552	WP_000414205.1	hypothetical protein	-
FZC51_RS02275	470321..470665	-	345	WP_000627551.1	DUF3969 family protein	-
FZC51_RS02280	470706..471332	-	627	Protein_438	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T138588 WP_001801861.1 NZ_CP043389:c466992-466897 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T138588 NZ_CP058160:c2282936-2282451 [Enterobacter hormaechei]
GTGGGACGTGTAACAGCACCAGAGCCGTTATCCAGCGCCCATCAACTGGCAGAGTTCGTCAGTGGAGAGGCCGTGCTTGA
CGAATGGCTAAAACAAAGAGGTCTAAAAAACCAGGCGCTCGGCGCAGCCCGAACGTTTGTCGTTTGTAAAACGGGCACGA
AGCAGGTCGCGGGATTTTACTCTCTGGCTACCGGCAGCGTTAACCATACGCAAGCGACAGGGAATCTGCGGCGTAACATG
CCGGATCCCATTCCCGTGATTATTCTTGCCCGTCTGGCTGTCGATGTCTCGTTACGCGGAAACGGGTTGGGAGCCGATTT
ACTCCACGATGCGGTTTTACGCTGTTATCGGGTAGCTGAGAATATCGGGGTGCGGGCGATTATGGTTCATGCACTCACTG
AGGAAGCCAAAGCGTTTTATATCCACCATGGTTTTAAAGCATCGCAGACTCAGGAACGGACACTGTTTCTCAGGCTTCCT
CAGTAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT138588 NZ_CP043389:466810-466869 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin