Detailed information of TA system TA138573

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1935438..1935620
• Replicon: chromosome
• Accession: NZ_CP043386
• Organism: Staphylococcus aureus strain NRS384

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: FZC49_RS09635
• Protein ID: WP_001801861.1
• Coordinates: 1935438..1935533 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1935561..1935620 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FZC49_RS09585	1931098..1931724	+	627	Protein_1845	hypothetical protein	-
FZC49_RS09590	1931765..1932109	+	345	WP_000627551.1	DUF3969 family protein	-
FZC49_RS09595	1932207..1932758	+	552	WP_000414205.1	hypothetical protein	-
FZC49_RS09600	1932976..1933617	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
FZC49_RS09605	1933731..1933916	-	186	WP_000809857.1	hypothetical protein	-
FZC49_RS09610	1933918..1934094	-	177	WP_000375476.1	hypothetical protein	-
FZC49_RS09615	1934105..1934488	-	384	WP_000070811.1	hypothetical protein	-
FZC49_RS09625	1935092..1935235	-	144	WP_001549059.1	transposase	-
FZC49_RS09635	1935438..1935533	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1935561..1935620	-	60	-	-	Antitoxin
FZC49_RS09640	1935656..1935757	+	102	WP_001791893.1	hypothetical protein	-
FZC49_RS09645	1935735..1935911	-	177	Protein_1855	transposase	-
FZC49_RS09650	1936105..1936482	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T138573 WP_001801861.1 NZ_CP043386:1935438-1935533 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T138573 NZ_CP058157:3802491-3802832 [Enterobacter hormaechei]
ATGAAAACTTTACCTGCAACAACTCAGCGGGCGGTGAAGCCCTGCCTGTCACCCGTGGCTGTCTGGCAAATGTTACTGAC
ACGTCTGCTGGAACAGCACTATGGTCTGACAATAAACGACACGCCATTCTGCAATGAGGCTGTGATTAAGGAACACATCG
ATGCCGGTATCACCCTAGCCGATGCCGTGAATTTTCTGGTAGAAAAATACGAGCTGGTTCGTATCGACAGGAAGGGATTT
AGCTGGCAGGAACAATCTCCTTATCTCCGGGCTGCAGACATTCTGCGAGCGCGGCAGGCAACTGGCTTGTTGCGGCAAAG
CCGTAACAACGTAGTACGATGA

Antitoxin

Nucleotide

• Length: 60 bp

>AT138573 NZ_CP043386:c1935620-1935561 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin