Detailed information of TA system TA138328

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/-
• Location: 538817..539484
• Replicon: chromosome
• Accession: NZ_CP043311
• Organism: Pseudomonas lalkuanensis strain PE08

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: FXN65_RS02515
• Protein ID: WP_151131512.1
• Coordinates: 539128..539484 (-)
• Length: 119 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: FXN65_RS02510
• Protein ID: WP_151131511.1
• Coordinates: 538817..539131 (-)
• Length: 105 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FXN65_RS02485	534556..535644	-	1089	WP_151131507.1	ABC transporter ATP-binding protein	-
FXN65_RS02490	535787..536476	+	690	WP_151131508.1	GntR family transcriptional regulator	-
FXN65_RS02495	536485..537222	+	738	WP_151131509.1	aspartate/glutamate racemase family protein	-
FXN65_RS02500	537192..537785	-	594	WP_178119264.1	phage antirepressor	-
FXN65_RS02505	538106..538603	+	498	WP_151131510.1	DUF1543 domain-containing protein	-
FXN65_RS02510	538817..539131	-	315	WP_151131511.1	transcriptional regulator	Antitoxin
FXN65_RS02515	539128..539484	-	357	WP_151131512.1	toxin	Toxin
FXN65_RS02525	539752..543489	-	3738	WP_151131513.1	PAS domain S-box protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 119 a.a.
• Molecular weight: 13610.56 Da
• Isoelectric Point: 10.0935

>T138328 WP_151131512.1 NZ_CP043311:c539484-539128 [Pseudomonas lalkuanensis]
MEALFVELPPFQRHRTDHLDDDAYAALQHLLLTQPDAGNLIQGTGGLRKLRFADEGRGKGKGKGKRSGIRVIYYWWLGGA
QFWLFTLYGKDVREYLSAAQKKVFRQRLEAELETRKTE

Nucleotide

• Length: 357 bp

>T138328 NZ_CP057566:2255-2536 [Escherichia fergusonii]
ATGATGGATATATTCTGGACCAGGCTGGCCAGCCAGGACAGAAAGCGCATTCGTGAGTACATTGCGGAGCAGAACCTGAT
GGCCGCCATTGAACTGGACGAACGGATTGGTTATTCAGCCAGCAGCCTGGCCGGGCAGCCGTATAAAGGCCGCAACGGTC
GTGTGGAAGGAACCCGGGAACTGGTTATTCACTCCCATTTTGTTCTGGTTTATGAAGTCGACAGCCAGTGGGGAAAAGTG
TATATCCTGCGCGTATTGCATACCGCACAGAAGTGGCCATAG

Antitoxin

Protein

• Length: 105 a.a.
• Molecular weight: 12023.94 Da
• Isoelectric Point: 8.6049

>AT138328 WP_151131511.1 NZ_CP043311:c539131-538817 [Pseudomonas lalkuanensis]
MKRDIFAELVEGIEALAEEREGKLTLRSHRLILPELRAVTAEELVSIRERLKMSRPVFAMYLRTNPRTLENWEQGRAKPN
AQATTLIRLVQQYPETVEHLATLA

Nucleotide

• Length: 315 bp

>AT138328 NZ_CP057566:1989-2258 [Escherichia fergusonii]
ATGGCACAGGTTAATATGAGTTTAAGAATCGACGCTGAACTGAAGGATGCTTTTATGGCCGCTGCAAAAAGCATGGACCG
TAATGGCTCTCAGTTAATCCGGGATTTTATGCGTCAGACTGTTGAACGGCAGCATAATACCTGGTTCCGTGACCAGGTTG
CGGAAGGACGTCAGCAACTCGAACGCGGTGATGTGCTTCCCCATGACATAGTCGAATCCTCCGCTGCTGCATGGCGGGAT
GAGATGAGCAGGAAGGTTGCCGGTAAATGA