Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 1765421..1765684 Replicon chromosome
Accession NZ_CP043302
Organism Staphylococcus aureus strain 16445

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FQP84_RS09050 Protein ID WP_001802298.1
Coordinates 1765421..1765525 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 1765520..1765684 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FQP84_RS09025 1760805..1761587 + 783 WP_000908176.1 ABC transporter ATP-binding protein -
FQP84_RS09030 1761655..1762512 + 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
FQP84_RS09035 1763217..1763309 - 93 WP_001790138.1 hypothetical protein -
FQP84_RS09040 1763598..1764734 + 1137 WP_000115564.1 SAP domain-containing protein -
FQP84_RS09045 1764777..1765260 + 484 Protein_1730 recombinase family protein -
FQP84_RS09050 1765421..1765525 + 105 WP_001802298.1 hypothetical protein Toxin
- 1765520..1765684 - 165 - - Antitoxin
FQP84_RS09055 1765968..1767059 - 1092 WP_000495671.1 lytic regulatory protein -
FQP84_RS09060 1767325..1768305 - 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
FQP84_RS09065 1768307..1768627 - 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FQP84_RS09070 1768779..1769444 + 666 WP_001024094.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T138308 WP_001802298.1 NZ_CP043302:1765421-1765525 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T138308 NZ_CP043302:1765421-1765525 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT138308 NZ_CP043302:c1765684-1765520 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References