Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3097558..3097804 Replicon chromosome
Accession NZ_CP043262
Organism Escherichia albertii strain RM9976

Toxin (Protein)


Gene name hokX Uniprot ID S1PD89
Locus tag FYK19_RS15485 Protein ID WP_000956458.1
Coordinates 3097558..3097710 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokX
Locus tag -
Coordinates 3097752..3097804 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYK19_RS15460 3092825..3093148 - 324 WP_001246114.1 DUF3561 family protein -
FYK19_RS15465 3093198..3093803 - 606 WP_262939557.1 adenylyl-sulfate kinase -
FYK19_RS15470 3093803..3095230 - 1428 WP_262939535.1 sulfate adenylyltransferase subunit CysN -
FYK19_RS15475 3095232..3096140 - 909 WP_161538128.1 sulfate adenylyltransferase subunit CysD -
FYK19_RS15480 3096395..3097432 + 1038 WP_059268554.1 alkaline phosphatase isozyme conversion aminopeptidase -
FYK19_RS15485 3097558..3097710 - 153 WP_000956458.1 Hok/Gef family protein Toxin
- 3097752..3097804 + 53 - - Antitoxin
FYK19_RS15490 3097975..3098709 - 735 WP_161538127.1 phosphoadenosine phosphosulfate reductase -
FYK19_RS15495 3098794..3100506 - 1713 WP_161538126.1 assimilatory sulfite reductase (NADPH) hemoprotein subunit -
FYK19_RS15500 3100506..3102305 - 1800 WP_262939536.1 NADPH-dependent assimilatory sulfite reductase flavoprotein subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(5-46)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5558.77 Da        Isoelectric Point: 7.6757

>T138079 WP_000956458.1 NZ_CP043262:c3097710-3097558 [Escherichia albertii]
MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK

Download         Length: 153 bp

>T138079 NZ_CP043262:c3097710-3097558 [Escherichia albertii]
ATGCTAACAAAATATGCCCTTGTGGCAATCATAGTGCTGTGTTGTACAGTGCTGGGATTCACGCTGATGGTAGGCGACTC
GTTGTGTGAGTTGAGTATCAGAGAACGTGGTATGGAGTTTAAGGCAGTTCTCGCTTACGAATCGAAGAAGTAG

Antitoxin


Download         Length: 53 bp

>AT138079 NZ_CP043262:3097752-3097804 [Escherichia albertii]
TTAGGTTCGAACGCTGGCCTCAGGTTGATAGAAATATCGCCTGGGGCTTTTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TJ83

Antitoxin

Download structure file

References