Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 15572..15830 Replicon chromosome
Accession NZ_CP043262
Organism Escherichia albertii strain RM9976

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag FYK19_RS00075 Protein ID WP_000809168.1
Coordinates 15572..15724 (-) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 15773..15830 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYK19_RS00055 10814..11527 - 714 WP_001102345.1 acidic protein MsyB -
FYK19_RS00060 11554..11958 - 405 WP_000833521.1 DUF2541 family protein -
FYK19_RS00065 12333..14249 + 1917 WP_000516135.1 molecular chaperone DnaK -
FYK19_RS00070 14338..15468 + 1131 WP_001118445.1 molecular chaperone DnaJ -
FYK19_RS00075 15572..15724 - 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
- 15773..15830 + 58 - - Antitoxin
FYK19_RS00080 16347..17108 + 762 WP_059216553.1 outer membrane protein OmpK -
FYK19_RS00085 17129..18622 + 1494 WP_059216552.1 sulfatase-like hydrolase/transferase -
FYK19_RS00090 18776..20023 + 1248 WP_059227922.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T138063 WP_000809168.1 NZ_CP043262:c15724-15572 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

>T138063 NZ_CP057243:1016985-1017137 [Escherichia fergusonii]
ATGCTGACAAAATATGCCCTTGTGGCAATCATCGTACTGTGTTGTACAGTACTGGGATTCACGCTGATGGTAGGCGACTC
GTTGTGTGAGTTGAGTATCAGAGAACGTGGTATGGAGTTTAAGGCAGTTCTCGCTTACGAATCGAAGAAGTAG

Antitoxin


Download         Length: 58 bp

>AT138063 NZ_CP043262:15773-15830 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References