Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 183530..183752 Replicon chromosome
Accession NZ_CP043183
Organism Escherichia coli O16:H48 strain PG20180172

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag FYA19_RS00890 Protein ID WP_000141634.1
Coordinates 183645..183752 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 183530..183596 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FYA19_RS00865 178971..179873 + 903 WP_000084677.1 dipeptide ABC transporter permease DppC -
FYA19_RS00870 179884..180867 + 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
FYA19_RS00875 180864..181868 + 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
FYA19_RS00880 181898..183169 - 1272 WP_001295225.1 transporter -
- 183530..183596 - 67 - - Antitoxin
FYA19_RS00890 183645..183752 + 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
FYA19_RS00895 183839..185518 - 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
FYA19_RS00900 185515..185706 - 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
FYA19_RS00905 185703..187274 - 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
FYA19_RS00910 187547..187735 + 189 WP_001063318.1 YhjR family protein -
FYA19_RS00915 187747..188499 + 753 Protein_176 cellulose biosynthesis protein BcsQ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T137391 WP_000141634.1 NZ_CP043183:183645-183752 [Escherichia coli O16:H48]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T137391 NZ_CP043183:183645-183752 [Escherichia coli O16:H48]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT137391 NZ_CP043183:c183596-183530 [Escherichia coli O16:H48]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References