Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 8889463..8890082 Replicon chromosome
Accession NZ_CP042997
Organism Aquisphaera giovannonii strain OJF2

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag OJF2_RS32810 Protein ID WP_148597594.1
Coordinates 8889765..8890082 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag OJF2_RS32805 Protein ID WP_148597593.1
Coordinates 8889463..8889768 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OJF2_RS32785 8885997..8886956 + 960 WP_148597589.1 ATP-binding cassette domain-containing protein -
OJF2_RS32790 8886946..8888340 + 1395 WP_148597590.1 ABC transporter permease -
OJF2_RS32795 8888463..8888726 - 264 WP_148597591.1 hypothetical protein -
OJF2_RS32800 8888753..8889403 - 651 WP_148597592.1 ceramidase domain-containing protein -
OJF2_RS32805 8889463..8889768 - 306 WP_148597593.1 helix-turn-helix domain-containing protein Antitoxin
OJF2_RS32810 8889765..8890082 - 318 WP_148597594.1 hypothetical protein Toxin
OJF2_RS32815 8890262..8891578 - 1317 WP_148597595.1 6-phosphofructokinase -
OJF2_RS32820 8891912..8892598 - 687 WP_148597596.1 hypothetical protein -
OJF2_RS32825 8892725..8893810 - 1086 WP_148597597.1 DUF1559 domain-containing protein -
OJF2_RS32830 8893919..8894173 - 255 WP_148597598.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(37-72)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11858.59 Da        Isoelectric Point: 9.4763

>T136895 WP_148597594.1 NZ_CP042997:c8890082-8889765 [Aquisphaera giovannonii]
MRFIETSIFTRVIGGLLDDEGFRALQLALLLAPRAGSVIPGSGGLRKMRWASGGGGKRGGCRVIYHWHEPSETYYLLYAY
RKNEQEDLTGEQIQALGRIVREEFR

Download         Length: 318 bp

>T136895 NZ_CP042997:c8890082-8889765 [Aquisphaera giovannonii]
ATGAGGTTCATCGAGACCTCGATCTTCACGCGGGTGATCGGCGGGCTTCTCGACGACGAGGGTTTTCGGGCCCTGCAGCT
GGCCTTGCTCCTCGCACCGAGAGCCGGCTCGGTCATCCCCGGGAGCGGAGGCCTTCGCAAGATGCGATGGGCGTCGGGTG
GAGGCGGCAAGCGCGGCGGGTGTCGGGTCATCTATCACTGGCACGAGCCGAGTGAGACCTATTACCTGCTCTATGCCTAT
CGCAAGAATGAACAGGAGGACTTGACCGGCGAACAGATCCAGGCCCTTGGCCGGATCGTTCGCGAGGAGTTCCGATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11174.70 Da        Isoelectric Point: 9.0921

>AT136895 WP_148597593.1 NZ_CP042997:c8889768-8889463 [Aquisphaera giovannonii]
MRAEDFDELVMSVREAGRIRRGEAQASRITDFAPVDVQAIRLRLAKSQSEFARMIGVSVATLQNWEAGRRRPEGPARALL
RVAAENPELVAAVLDPTSRDS

Download         Length: 306 bp

>AT136895 NZ_CP042997:c8889768-8889463 [Aquisphaera giovannonii]
ATGAGAGCCGAGGATTTCGATGAGCTGGTGATGAGCGTCCGCGAAGCCGGCCGGATCCGTAGGGGCGAGGCGCAGGCGAG
CCGCATCACCGATTTTGCTCCCGTGGATGTTCAGGCCATTCGCCTGCGGCTGGCCAAGTCCCAATCCGAGTTCGCTCGGA
TGATCGGAGTGAGCGTGGCCACCCTGCAGAATTGGGAGGCGGGGCGTCGCAGGCCCGAGGGGCCTGCCCGTGCCCTCTTG
AGGGTCGCGGCCGAGAATCCGGAGCTGGTCGCCGCCGTCCTCGATCCGACGAGTCGGGATTCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References