Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_31
Location 4039974..4040575 Replicon chromosome
Accession NZ_CP042968
Organism Bradyrhizobium paxllaeri strain LMTR 21

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LMTR21_RS19315 Protein ID WP_065753989.1
Coordinates 4039974..4040297 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LMTR21_RS19320 Protein ID WP_065753988.1
Coordinates 4040294..4040575 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LMTR21_RS19300 4036368..4037267 + 900 WP_065756753.1 DMT family transporter -
LMTR21_RS19305 4037335..4038480 - 1146 WP_148635931.1 IS4 family transposase -
LMTR21_RS19310 4038792..4039856 + 1065 WP_065753990.1 hypothetical protein -
LMTR21_RS19315 4039974..4040297 + 324 WP_065753989.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LMTR21_RS19320 4040294..4040575 + 282 WP_065753988.1 helix-turn-helix transcriptional regulator Antitoxin
LMTR21_RS19325 4040972..4041304 - 333 WP_065753986.1 HNH endonuclease -
LMTR21_RS19330 4041402..4043636 - 2235 WP_065753985.1 CHASE3 domain-containing protein -
LMTR21_RS19335 4043655..4044059 - 405 WP_065754000.1 response regulator -
LMTR21_RS19340 4044235..4045125 + 891 WP_065753984.1 DMT family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(15-104)

Antitoxin

Cro/C1-type helix-turn-helix domain

(35-83)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12056.09 Da        Isoelectric Point: 11.0079

>T136744 WP_065753989.1 NZ_CP042968:4039974-4040297 [Bradyrhizobium paxllaeri]
VAWRVEILNESVAAEIASLPSDMQARFLRLAERISLAGLESLSEPHVKHLEGKLWELRLTGRDGIARALYVTAIGRRVVI
VRAFAKKTQKTPRSEIELALQRAKEVR

Download         Length: 324 bp

>T136744 NZ_CP042968:4039974-4040297 [Bradyrhizobium paxllaeri]
GTGGCTTGGCGGGTAGAAATCCTGAACGAATCGGTCGCTGCGGAAATCGCTTCCCTTCCGAGTGACATGCAGGCGCGGTT
TCTGCGACTAGCAGAACGCATCAGCTTAGCTGGGCTAGAAAGCCTGAGCGAGCCGCACGTCAAACATCTCGAAGGGAAGC
TATGGGAGTTGCGGCTGACAGGTCGTGACGGAATTGCTCGCGCGCTTTATGTCACGGCGATCGGCCGAAGGGTGGTCATA
GTTCGCGCATTTGCAAAGAAAACTCAAAAGACCCCACGCTCGGAGATCGAGCTCGCGCTGCAGCGAGCAAAGGAGGTCAG
ATGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10257.94 Da        Isoelectric Point: 10.8350

>AT136744 WP_065753988.1 NZ_CP042968:4040294-4040575 [Bradyrhizobium paxllaeri]
MTIPFEKIKARLLTNPKVKAEYEALAPEFEIAAELLRARLRAGLSQAELAARMRTSQSTIARLESGQTLPSTKTLLRYAE
ATGSKFHVRLSAA

Download         Length: 282 bp

>AT136744 NZ_CP042968:4040294-4040575 [Bradyrhizobium paxllaeri]
ATGACAATTCCGTTTGAAAAGATCAAAGCTCGTCTCTTGACCAATCCGAAGGTGAAGGCGGAGTACGAGGCGCTCGCTCC
AGAGTTCGAAATTGCCGCCGAGTTGCTCAGGGCTCGCCTGCGCGCGGGTCTCTCGCAAGCCGAACTGGCTGCCCGGATGA
GGACCAGCCAATCCACGATCGCACGACTTGAAAGCGGTCAAACGTTACCGAGCACGAAGACACTGCTGCGCTATGCTGAA
GCAACCGGTAGTAAGTTTCACGTGCGGCTGTCGGCGGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References