Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-VapI
Location 3032574..3033182 Replicon chromosome
Accession NZ_CP042968
Organism Bradyrhizobium paxllaeri strain LMTR 21

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag LMTR21_RS14270 Protein ID WP_065750138.1
Coordinates 3032574..3032858 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LMTR21_RS14275 Protein ID WP_065750139.1
Coordinates 3032871..3033182 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LMTR21_RS14250 3028387..3029724 + 1338 WP_065750134.1 replication-associated recombination protein A -
LMTR21_RS14255 3029721..3030437 + 717 WP_065750135.1 tetratricopeptide repeat protein -
LMTR21_RS14260 3030482..3031282 - 801 WP_065750136.1 LON peptidase substrate-binding domain-containing protein -
LMTR21_RS14265 3031497..3032441 - 945 WP_065750137.1 alpha/beta hydrolase -
LMTR21_RS14270 3032574..3032858 + 285 WP_065750138.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LMTR21_RS14275 3032871..3033182 + 312 WP_065750139.1 HigA family addiction module antidote protein Antitoxin
LMTR21_RS14280 3033190..3034392 + 1203 WP_065750140.1 RluA family pseudouridine synthase -
LMTR21_RS14285 3034494..3035711 + 1218 WP_141688032.1 amidohydrolase family protein -
LMTR21_RS14290 3035908..3036681 + 774 WP_065750141.1 ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-64)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10598.94 Da        Isoelectric Point: 6.4565

>T136742 WP_065750138.1 NZ_CP042968:3032574-3032858 [Bradyrhizobium paxllaeri]
MIVSYRDKRTERFASGRHVKEFSGFARQAETRLDRLDAATSLADLAALPGNRLEALRGDCAGLFSIRINDQWRICFAWPE
GSSGPIEVEIVDYH

Download         Length: 285 bp

>T136742 NZ_CP042968:3032574-3032858 [Bradyrhizobium paxllaeri]
ATGATCGTCAGTTATCGGGACAAGCGCACCGAGCGGTTTGCCTCAGGACGCCACGTCAAGGAATTCTCCGGCTTCGCGCG
ACAGGCCGAGACGCGTCTCGATCGACTGGATGCGGCGACCAGCTTGGCTGATCTGGCGGCGCTGCCCGGCAACCGTCTGG
AAGCACTCAGGGGTGACTGTGCCGGACTGTTTTCGATTCGTATCAACGATCAGTGGCGAATTTGCTTCGCCTGGCCGGAA
GGATCGTCCGGCCCGATCGAGGTGGAAATTGTGGACTATCACTGA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11513.14 Da        Isoelectric Point: 10.3694

>AT136742 WP_065750139.1 NZ_CP042968:3032871-3033182 [Bradyrhizobium paxllaeri]
MPRSPIHPGEHLAEELQELGITAAELSRQIDVPVNRITGIIHGQRGITADTALRLGHWFGTSPQFWMNLQQLYELRLAEN
EVGAKIAALPRRAGRPNSRQVRS

Download         Length: 312 bp

>AT136742 NZ_CP042968:3032871-3033182 [Bradyrhizobium paxllaeri]
ATGCCTCGCTCTCCCATTCATCCCGGTGAGCATCTTGCTGAAGAACTGCAGGAGCTCGGAATCACTGCTGCGGAGCTTTC
GCGTCAGATCGACGTGCCGGTAAACCGGATTACGGGCATCATTCACGGTCAGCGCGGCATCACCGCCGACACGGCATTAC
GGCTGGGGCACTGGTTTGGCACCAGCCCGCAATTCTGGATGAATTTGCAGCAGCTCTACGAACTGCGTCTCGCCGAAAAC
GAAGTTGGCGCGAAGATCGCAGCGTTGCCGCGTCGGGCCGGCCGACCGAACTCGCGACAAGTCCGGAGCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References