Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 3788415..3789124 Replicon chromosome
Accession NZ_CP042941
Organism Atlantibacter hermannii strain ATCC 33651

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag FV157_RS17645 Protein ID WP_148052784.1
Coordinates 3788819..3789124 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag FV157_RS17640 Protein ID WP_148053110.1
Coordinates 3788415..3788819 (-) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FV157_RS17620 3784229..3785803 + 1575 WP_148052783.1 urea ABC transporter permease subunit UrtB -
FV157_RS17625 3785803..3786876 + 1074 WP_040459851.1 urea ABC transporter permease subunit UrtC -
FV157_RS17630 3786876..3787673 + 798 WP_040459852.1 urea ABC transporter ATP-binding protein UrtD -
FV157_RS17635 3787683..3788381 + 699 WP_002435657.1 urea ABC transporter ATP-binding subunit UrtE -
FV157_RS17640 3788415..3788819 - 405 WP_148053110.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
FV157_RS17645 3788819..3789124 - 306 WP_148052784.1 type II toxin-antitoxin system MqsR family toxin Toxin
FV157_RS17650 3789204..3790391 - 1188 WP_148052785.1 efflux MFS transporter YdeE -
FV157_RS17655 3790590..3791486 + 897 WP_148052786.1 O-acetylserine/cysteine exporter -
FV157_RS17665 3792452..3792661 - 210 WP_043864941.1 multiple antibiotic resistance regulatory protein MarB -
FV157_RS17670 3792694..3793068 - 375 WP_002435664.1 MDR efflux pump AcrAB transcriptional activator MarA -
FV157_RS17675 3793086..3793520 - 435 WP_040459814.1 multiple antibiotic resistance transcriptional regulator MarR -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(3-100)

Antitoxin

Zinc finger, MqsA-type

(4-49)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11666.77 Da        Isoelectric Point: 9.4481

>T136656 WP_148052784.1 NZ_CP042941:c3789124-3788819 [Atlantibacter hermannii]
MRKGTPNVPLSVVKEMVRSGKVKTTFTATQGALELGFPAPVLPLMCKIVLLLDQSHFYKSMTAYHDETIWHDVYRTRFDE
RHIYLKLIVKDDVLIVSFKEL

Download         Length: 306 bp

>T136656 NZ_CP042941:c3789124-3788819 [Atlantibacter hermannii]
ATGAGAAAAGGAACACCCAACGTCCCTCTGAGCGTGGTGAAAGAAATGGTGCGGTCAGGCAAAGTCAAAACCACCTTTAC
CGCCACGCAAGGCGCGCTTGAATTAGGCTTCCCCGCGCCAGTGTTACCCTTAATGTGCAAAATTGTTTTGCTGCTGGACC
AGAGTCATTTTTATAAAAGTATGACTGCGTATCATGATGAAACCATCTGGCATGATGTGTATCGCACGCGTTTCGACGAA
CGCCATATCTATCTTAAGCTTATCGTGAAAGATGACGTCCTGATTGTGTCATTTAAGGAGTTATGA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 14911.93 Da        Isoelectric Point: 7.6663

>AT136656 WP_148053110.1 NZ_CP042941:c3788819-3788415 [Atlantibacter hermannii]
MKTCSVCGGGHLTHESRDLPYEYKGSKTTLRGIVGEYCNSCGEIIFTPEESNAFSAQASAFRTAVNAESFDPTLFTRVRK
NLRIDQQQAGMLFGGGVNAFSRYETGKTTPPIAVVKLFKMFDKFPELFEEYKSL

Download         Length: 405 bp

>AT136656 NZ_CP042941:c3788819-3788415 [Atlantibacter hermannii]
ATGAAAACTTGTTCCGTTTGTGGCGGCGGCCATTTAACTCATGAAAGCCGCGATCTGCCCTATGAATACAAAGGCAGCAA
AACAACCTTGCGTGGGATTGTTGGCGAATATTGCAATTCCTGCGGTGAAATTATCTTTACTCCTGAAGAAAGCAACGCCT
TTAGCGCTCAGGCCTCAGCCTTCCGCACTGCGGTGAATGCAGAATCTTTCGACCCGACGCTGTTTACCCGGGTGCGTAAA
AATTTGCGCATCGATCAGCAACAGGCCGGTATGCTGTTTGGCGGCGGCGTAAATGCCTTTTCACGTTATGAAACCGGGAA
AACCACGCCGCCGATAGCCGTGGTGAAACTCTTTAAAATGTTTGATAAGTTCCCGGAATTATTCGAAGAATACAAATCGC
TGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References