136109

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 4408572..4408794 Replicon chromosome
Accession NZ_CP042843
Organism Escherichia coli strain JME67

Toxin (Protein)


Gene name ldrD Uniprot ID S1E8T8
Locus tag FVE23_RS21420 Protein ID WP_000141634.1
Coordinates 4408572..4408679 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 4408728..4408794 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FVE23_RS21395 4403825..4404577 - 753 Protein_4130 cellulose biosynthesis protein BcsQ -
FVE23_RS21400 4404589..4404777 - 189 WP_001063318.1 YhjR family protein -
FVE23_RS21405 4405050..4406621 + 1572 WP_001204931.1 cellulose biosynthesis protein BcsE -
FVE23_RS21410 4406618..4406809 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
FVE23_RS21415 4406806..4408485 + 1680 WP_000191622.1 cellulose biosynthesis protein BcsG -
FVE23_RS21420 4408572..4408679 - 108 WP_000141634.1 type I toxin-antitoxin system toxic polypeptide LdrD Toxin
- 4408728..4408794 + 67 - - Antitoxin
FVE23_RS21430 4409155..4410426 + 1272 WP_001295225.1 transporter -
FVE23_RS21435 4410456..4411460 - 1005 WP_000107012.1 dipeptide ABC transporter ATP-binding subunit DppF -
FVE23_RS21440 4411457..4412440 - 984 WP_001196486.1 dipeptide ABC transporter ATP-binding protein -
FVE23_RS21445 4412451..4413353 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3916.72 Da        Isoelectric Point: 9.0157

>T136109 WP_000141634.1 NZ_CP042843:c4408679-4408572 [Escherichia coli]
MTFAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T136109 NZ_CP042843:c4408679-4408572 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 67 bp

>AT136109 NZ_CP042843:4408728-4408794 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 5LBJ

Antitoxin

Download structure file

References