Detailed information of TA system TA136048

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mqsRA (relBE)/MqsR-MqsA
• Location: 568405..569132
• Replicon: plasmid unnamed2
• Accession: NZ_CP042825
• Organism: Rhizobium sp. WL3

Toxin (Protein)

• Gene name: mqsR
• Uniprot ID: -
• Locus tag: FVA81_RS03075
• Protein ID: WP_147885202.1
• Coordinates: 568405..568710 (+)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: mqsA
• Uniprot ID: -
• Locus tag: FVA81_RS03080
• Protein ID: WP_147885203.1
• Coordinates: 568713..569132 (+)
• Length: 140 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FVA81_RS03050	563848..564684	-	837	WP_147885198.1	carbohydrate ABC transporter permease	-
FVA81_RS03055	564681..565616	-	936	WP_147885199.1	sugar ABC transporter permease	-
FVA81_RS03060	565609..566778	-	1170	WP_147885200.1	ABC transporter ATP-binding protein	-
FVA81_RS03065	566775..567611	-	837	WP_147885201.1	metallophosphoesterase	-
FVA81_RS03070	568073..568249	+	177	Protein_529	DUF1738 domain-containing protein	-
FVA81_RS03075	568405..568710	+	306	WP_147885202.1	type II toxin-antitoxin system MqsR family toxin	Toxin
FVA81_RS03080	568713..569132	+	420	WP_147885203.1	type II toxin-antitoxin system MqsA family antitoxin	Antitoxin
FVA81_RS03085	569617..569856	+	240	Protein_532	nucleotidyl transferase AbiEii/AbiGii toxin family protein	-
FVA81_RS25610	570154..570483	-	330	WP_187181995.1	hypothetical protein	-
FVA81_RS03095	570522..570704	+	183	WP_147885204.1	hypothetical protein	-
FVA81_RS03100	570711..571481	+	771	WP_147885205.1	exodeoxyribonuclease III	-
FVA81_RS03105	571485..571835	+	351	WP_147885206.1	hypothetical protein	-
FVA81_RS03110	572026..572499	+	474	WP_147885207.1	hypothetical protein	-
FVA81_RS03115	572548..574077	-	1530	WP_187181996.1	PAS domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Conjugative plasmid	-	gmd	1..700631	700631

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase toxin MqsR (3-100)

Antitoxin

• Antitoxin MqsA/HigA-2 (1-132)

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 11400.92 Da
• Isoelectric Point: 4.3280

>T136048 WP_147885202.1 NZ_CP042825:568405-568710 [Rhizobium sp. WL3]
MTEKKVAHYPLEDVFACIAEDDVRATNTAYDGADDLGIETLDEMCTIIKKLTVGDLHKSMTTHADDTIWQDVYRPFIDSE
TQAYIKLTITNGLLIVSFKEK

Nucleotide

• Length: 306 bp

>T136048 NZ_CP042825:568405-568710 [Rhizobium sp. WL3]
ATGACAGAAAAGAAGGTCGCCCACTATCCGTTGGAGGATGTCTTCGCTTGTATCGCTGAAGACGACGTCCGCGCCACCAA
CACTGCTTACGATGGAGCCGATGATCTCGGAATCGAAACGCTTGATGAAATGTGCACGATCATCAAGAAGCTGACAGTCG
GAGACCTACACAAGTCGATGACAACACATGCGGACGATACGATATGGCAGGACGTTTACCGCCCTTTTATTGATTCGGAA
ACGCAAGCCTATATCAAGCTGACTATAACGAACGGACTTTTGATTGTGTCCTTTAAGGAGAAGTGA

Antitoxin

Protein

• Length: 140 a.a.
• Molecular weight: 15528.73 Da
• Isoelectric Point: 7.6683

>AT136048 WP_147885203.1 NZ_CP042825:568713-569132 [Rhizobium sp. WL3]
MKCPMCGGSELSHEIRDIPYTYKSKATVIKGVEGDFCASCDEVILDRLNGDRYGAEIRAFKRQVNEESGVDPAFIARVRK
KLDLDQKEAGRVFGGGDNAFSRYERGRAKPPVSLVKLLSLLDRHPELISEVKEEQIRAA

Nucleotide

• Length: 420 bp

>AT136048 NZ_CP042825:568713-569132 [Rhizobium sp. WL3]
ATGAAGTGCCCAATGTGCGGTGGTTCCGAATTGTCTCATGAAATACGGGACATCCCTTATACCTATAAGTCTAAGGCGAC
TGTGATCAAAGGCGTCGAGGGTGATTTCTGCGCTTCATGCGACGAAGTCATTCTCGACAGGTTGAACGGAGATCGCTATG
GCGCGGAAATCCGGGCGTTCAAGCGTCAGGTGAATGAAGAAAGCGGTGTCGATCCTGCGTTCATTGCCAGGGTTAGGAAA
AAACTTGATCTCGACCAGAAGGAAGCCGGACGCGTTTTTGGTGGAGGTGATAACGCCTTTTCACGGTATGAGCGTGGACG
TGCGAAGCCTCCGGTCTCATTGGTGAAGCTTCTGTCACTTCTGGACAGACATCCGGAACTGATCTCAGAAGTCAAAGAAG
AGCAAATCAGGGCGGCGTAG