Detailed information of TA system TA136027

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-RelB
• Location: 2683579..2684087
• Replicon: chromosome
• Accession: NZ_CP042652
• Organism: Pseudoarcobacter acticola strain KCTC 52212

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: AACT_RS13710
• Protein ID: WP_172127797.1
• Coordinates: 2683827..2684087 (+)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: AACT_RS13705
• Protein ID: WP_172127795.1
• Coordinates: 2683579..2683830 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AACT_RS13680	2678679..2679302	+	624	WP_172127785.1	glycerol-3-phosphate 1-O-acyltransferase PlsY	-
AACT_RS13685	2679328..2679639	+	312	WP_172127787.1	dihydroneopterin aldolase	-
AACT_RS13690	2680229..2681407	+	1179	WP_172127789.1	porin	-
AACT_RS13695	2681556..2682182	+	627	WP_172127791.1	c-type cytochrome	-
AACT_RS13700	2682324..2683451	+	1128	WP_172127793.1	porin	-
AACT_RS13705	2683579..2683830	+	252	WP_172127795.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
AACT_RS13710	2683827..2684087	+	261	WP_172127797.1	Txe/YoeB family addiction module toxin	Toxin
AACT_RS13715	2684624..2685718	+	1095	WP_172127799.1	peptide chain release factor 2	-
AACT_RS13720	2685745..2688114	-	2370	WP_172127801.1	PD-(D/E)XK nuclease family protein	-
AACT_RS13725	2688104..2688661	-	558	WP_172127803.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-86)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-72)

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 10443.00 Da
• Isoelectric Point: 8.8240

>T136027 WP_172127797.1 NZ_CP042652:2683827-2684087 [Pseudoarcobacter acticola]
MIIGFADEAWEDYQYWSLNDKNIFKRINLLIKDIKRNPFDANGLGKPERLKENFQGYFSRRITSEHRLVYKIIDDLIIIA
QCRYHY

Nucleotide

• Length: 261 bp

>T136027 NZ_CP042652:2683827-2684087 [Pseudoarcobacter acticola]
ATGATTATTGGATTTGCAGATGAAGCATGGGAAGATTATCAATATTGGTCTTTAAATGATAAAAATATATTCAAAAGAAT
AAATTTATTAATCAAAGATATAAAAAGAAATCCCTTCGATGCTAATGGACTTGGAAAACCAGAAAGACTAAAAGAAAATT
TTCAAGGATACTTTTCAAGAAGAATAACATCAGAACACAGACTAGTATATAAAATAATCGATGATTTGATAATCATAGCT
CAATGTAGATATCATTATTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9848.10 Da
• Isoelectric Point: 4.5112

>AT136027 WP_172127795.1 NZ_CP042652:2683579-2683830 [Pseudoarcobacter acticola]
MQAVFYSQARNNLREIINKVCDDFDEYIITTKDEKSVVLISYEEYSSMKETIYLLSSKNNRDRLNDAVEQIENSKFLKKE
IDL

Nucleotide

• Length: 252 bp

>AT136027 NZ_CP042652:2683579-2683830 [Pseudoarcobacter acticola]
ATGCAAGCAGTTTTTTACTCACAAGCAAGAAATAATCTAAGAGAAATTATAAATAAAGTATGTGATGATTTTGATGAATA
TATTATTACTACAAAAGATGAGAAATCTGTAGTTTTGATTTCATATGAAGAGTATAGTTCAATGAAAGAAACAATATATC
TTTTATCTTCAAAAAATAATAGAGATAGATTAAATGATGCCGTAGAACAAATAGAAAACTCAAAATTTCTTAAAAAAGAA
ATTGATTTATGA