Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2565335..2565519 Replicon chromosome
Accession NZ_CP042650
Organism Staphylococcus aureus strain X22

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag FTD94_RS13205 Protein ID WP_000482647.1
Coordinates 2565412..2565519 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2565335..2565395 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FTD94_RS13190 2560865..2561032 - 168 WP_001790576.1 hypothetical protein -
FTD94_RS13195 2561263..2562996 - 1734 WP_044291035.1 ABC transporter ATP-binding protein/permease -
FTD94_RS13200 2563021..2564784 - 1764 WP_044291037.1 ABC transporter ATP-binding protein/permease -
- 2565335..2565395 + 61 - - Antitoxin
FTD94_RS13205 2565412..2565519 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
FTD94_RS13210 2565653..2566039 - 387 WP_000779360.1 flippase GtxA -
FTD94_RS13215 2566297..2567439 + 1143 WP_001176863.1 glycerate kinase -
FTD94_RS13220 2567499..2568158 + 660 WP_000831298.1 membrane protein -
FTD94_RS13225 2568340..2569551 + 1212 WP_147091819.1 multidrug effflux MFS transporter -
FTD94_RS13230 2569692..2570147 - 456 WP_044291042.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - sbi / hlgA / hlgA / hlgC / hlgB 2550165..2568158 17993


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T136020 WP_000482647.1 NZ_CP042650:c2565519-2565412 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T136020 NZ_CP042650:c2565519-2565412 [Staphylococcus aureus]
ATGTTCAATTTATTAATTGACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT136020 NZ_CP042650:2565335-2565395 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References