136018

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-SprA2AS/-
Location 2284507..2284723 Replicon chromosome
Accession NZ_CP042650
Organism Staphylococcus aureus strain X22

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FTD94_RS11720 Protein ID WP_001802298.1
Coordinates 2284619..2284723 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2284507..2284562 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FTD94_RS11700 2280770..2281435 - 666 WP_001024095.1 SDR family oxidoreductase -
FTD94_RS11705 2281587..2281907 + 321 WP_000003755.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FTD94_RS11710 2281909..2282886 + 978 WP_006190804.1 CDF family zinc efflux transporter CzrB -
FTD94_RS11715 2283152..2284243 + 1092 WP_044290727.1 lytic regulatory protein -
- 2284507..2284562 + 56 - - Antitoxin
FTD94_RS11720 2284619..2284723 - 105 WP_001802298.1 hypothetical protein Toxin
FTD94_RS14955 2285240..2285410 + 171 WP_001792292.1 transposase -
FTD94_RS11730 2285403..2285561 + 159 WP_001792784.1 hypothetical protein -
FTD94_RS11740 2286220..2287077 - 858 WP_044290728.1 Cof-type HAD-IIB family hydrolase -
FTD94_RS11745 2287145..2287927 - 783 WP_044290729.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T136018 WP_001802298.1 NZ_CP042650:c2284723-2284619 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T136018 NZ_CP042650:c2284723-2284619 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT136018 NZ_CP042650:2284507-2284562 [Staphylococcus aureus]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References