Detailed information of TA system TA136008

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 964762..964988
• Replicon: chromosome
• Accession: NZ_CP042650
• Organism: Staphylococcus aureus strain X22

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: -
• Locus tag: FTD94_RS05030
• Protein ID: WP_115211349.1
• Coordinates: 964762..964866 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	964895..964988 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FTD94_RS05010	961343..961729	+	387	WP_000705912.1	DUF2977 domain-containing protein	-
FTD94_RS05015	961722..961877	+	156	WP_031766783.1	XkdX family protein	-
FTD94_RS05020	961962..962330	+	369	WP_102947779.1	hypothetical protein	-
FTD94_RS05025	962911..964680	+	1770	Protein_956	glucosaminidase domain-containing protein	-
FTD94_RS05030	964762..964866	+	105	WP_115211349.1	hypothetical protein	Toxin
-	964895..964988	-	94	NuclAT_1	-	Antitoxin
-	964895..964988	-	94	NuclAT_1	-	Antitoxin
-	964895..964988	-	94	NuclAT_1	-	Antitoxin
-	964895..964988	-	94	NuclAT_1	-	Antitoxin
FTD94_RS05035	964922..965017	-	96	Protein_958	hypothetical protein	-
FTD94_RS05040	965068..965505	+	438	WP_147091767.1	phage holin	-
FTD94_RS05045	965486..966931	+	1446	WP_147091768.1	SH3 domain-containing protein	-
FTD94_RS05050	967513..967755	+	243	WP_000725495.1	hypothetical protein	-
FTD94_RS05065	968438..968577	+	140	Protein_962	hypothetical protein	-
FTD94_RS05070	968583..968897	-	315	WP_000274029.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	921392..967931	46539

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3949.80 Da
• Isoelectric Point: 5.5724

>T136008 WP_115211349.1 NZ_CP042650:964762-964866 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIISLVLISNQDHKK

Nucleotide

• Length: 105 bp

>T136008 NZ_CP042650:964762-964866 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTAATGGTTGTTTTAACGATCATCAGTTTAGTATTAAT
CAGTAATCAAGACCATAAAAAATAA

Antitoxin

Nucleotide

• Length: 94 bp

>AT136008 NZ_CP042650:c964988-964895 [Staphylococcus aureus]
ATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGAGAGCCCGTTAAAAAGACGGTGGCTTTTCATAGAAAAA
TTATAAAAATAACC

Structures

Antitoxin