Detailed information of TA system TA136003

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-SprF1/-
• Location: 363514..363852
• Replicon: chromosome
• Accession: NZ_CP042650
• Organism: Staphylococcus aureus strain X22

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: FTD94_RS01745
• Protein ID: WP_147091840.1
• Coordinates: 363514..363690 (+)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	SprF1
Locus tag	-
Coordinates	363679..363852 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FTD94_RS01725	358858..362532	+	3675	WP_147091733.1	hypothetical protein	-
FTD94_RS01730	362522..362674	+	153	WP_001153680.1	hypothetical protein	-
FTD94_RS01735	362721..363008	+	288	WP_147091734.1	hypothetical protein	-
FTD94_RS01740	363066..363362	+	297	WP_060552603.1	DUF2951 domain-containing protein	-
FTD94_RS01745	363514..363690	+	177	WP_147091840.1	putative holin-like toxin	Toxin
-	363679..363852	-	174	-	-	Antitoxin
FTD94_RS01755	363901..364338	+	438	WP_147091735.1	phage holin	-
FTD94_RS01760	364319..365764	+	1446	WP_147091736.1	SH3 domain-containing protein	-
FTD94_RS01770	366158..366799	+	642	WP_147091737.1	DUF3800 domain-containing protein	-
FTD94_RS01775	366953..367255	+	303	Protein_346	SH3 domain-containing protein	-
FTD94_RS01785	368300..368506	+	207	WP_147091738.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	geh	321784..367255	45471

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (30-58)

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6821.39 Da
• Isoelectric Point: 10.6777

>T136003 WP_147091840.1 NZ_CP042650:363514-363690 [Staphylococcus aureus]
MDRWWLSEYKEVVPMAALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK

Nucleotide

• Length: 177 bp

>T136003 NZ_CP042650:363514-363690 [Staphylococcus aureus]
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGCGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGTAATAAAAAATAA

Antitoxin

Nucleotide

• Length: 174 bp

>AT136003 NZ_CP042650:c363852-363679 [Staphylococcus aureus]
ATTTGATATTTATATTATGATGTGTTAATTTATATATAGAAAAAGGGCAACATGCGGAAACATGTCACCCTAGTGAGCCC
GTTAAAAAGACGGTGGCTATTTTAGATTAAAGATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGAT
GGTTATTTTTTATT

Structures

Antitoxin