Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_37
Location 3923732..3924369 Replicon chromosome
Accession NZ_CP042596
Organism Granulicella sp. WH15

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag FTO74_RS16270 Protein ID WP_162539083.1
Coordinates 3924046..3924369 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag FTO74_RS16265 Protein ID WP_162539082.1
Coordinates 3923732..3924049 (-) Length 106 a.a.

Genomic Context

FTO74_RS16245FTO74_RS16255FTO74_RS16260FTO74_RS16275FTO74_RS16280FTO74_RS19405FTO74_RS16290FTO74_RS16250FTO74_RS16265FTO74_RS16270FTO74_RS16295FTO74_RS16300
Location: 3919210..3919980 (771 bp)
Type: Others
Protein ID: WP_162539078.1
Location: 3921754..3922002 (249 bp)
Type: Others
Protein ID: WP_162539080.1
Location: 3921999..3923231 (1233 bp)
Type: Others
Protein ID: WP_162539081.1
Location: 3924578..3924841 (264 bp)
Type: Others
Protein ID: WP_162539084.1
Location: 3924838..3925266 (429 bp)
Type: Others
Protein ID: WP_162539085.1
Location: 3925721..3926458 (738 bp)
Type: Others
Protein ID: WP_174242236.1
Location: 3926544..3926927 (384 bp)
Type: Others
Protein ID: WP_162539086.1
Location: 3920582..3921517 (936 bp)
Type: Others
Protein ID: WP_162539079.1
Location: 3923732..3924049 (318 bp)
Type: Antitoxin
Protein ID: WP_162539082.1
Location: 3924046..3924369 (324 bp)
Type: Toxin
Protein ID: WP_162539083.1
Location: 3926979..3927758 (780 bp)
Type: Others
Protein ID: WP_162539087.1
Location: 3927755..3928858 (1104 bp)
Type: Others
Protein ID: WP_162539088.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FTO74_RS162453919210..3919980+771WP_162539078.1MBL fold metallo-hydrolase-
FTO74_RS162503920582..3921517-936WP_162539079.1LysR family transcriptional regulator-
FTO74_RS162553921754..3922002+249WP_162539080.1helix-turn-helix domain-containing protein-
FTO74_RS162603921999..3923231+1233WP_162539081.1site-specific integrase-
FTO74_RS162653923732..3924049-318WP_162539082.1helix-turn-helix domain-containing proteinAntitoxin
FTO74_RS162703924046..3924369-324WP_162539083.1type II toxin-antitoxin system RelE/ParE family toxinToxin
FTO74_RS162753924578..3924841+264WP_162539084.1prevent-host-death protein-
FTO74_RS162803924838..3925266+429WP_162539085.1nucleotide-binding protein-
FTO74_RS194053925721..3926458+738WP_174242236.1ATP-binding domain-containing protein-
FTO74_RS162903926544..3926927+384WP_162539086.1hypothetical protein-
FTO74_RS162953926979..3927758-780WP_162539087.1LytTR family DNA-binding domain-containing protein-
FTO74_RS163003927755..3928858-1104WP_162539088.1histidine kinase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(15-104)

Antitoxin

Cro/C1-type helix-turn-helix domain

(39-89)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12302.46 Da        Isoelectric Point: 10.7402

>T136001 WP_162539083.1 NZ_CP042596:c3924369-3924046 [Granulicella sp. WH15]
MGWVVGFLNEEVKASLDAFPLDIRASFQRISELIQSHGLERVREPYVKHLEGPLWEMRMKGRSGIARACYVTAVGKRVVV
VHVFEKKTQKTPRREILTALKRAKEVQ

Download         Length: 324 bp

>T136001 NZ_CP042596:c3924369-3924046 [Granulicella sp. WH15]
ATGGGATGGGTGGTTGGATTTTTGAATGAAGAGGTAAAGGCATCGCTCGATGCGTTCCCTTTGGACATTCGAGCGAGCTT
CCAACGCATATCCGAATTGATTCAGTCGCATGGTCTGGAGCGGGTGCGGGAACCCTATGTGAAACACCTGGAGGGTCCGC
TGTGGGAGATGCGTATGAAGGGCAGGAGCGGAATTGCGCGGGCCTGTTATGTCACTGCCGTGGGGAAGCGGGTCGTCGTC
GTTCATGTCTTTGAGAAGAAAACGCAGAAAACACCAAGGCGGGAGATTCTAACCGCCCTCAAACGGGCAAAGGAGGTTCA
ATGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11783.46 Da        Isoelectric Point: 8.5277

>AT136001 WP_162539082.1 NZ_CP042596:c3924049-3923732 [Granulicella sp. WH15]
MKRKFIPAEESFAQWKKDPKYVAEYAALEEEFALASALIEARGNADMTQEEVAEAMGTTQAVVARLESGKVLPSTRTLER
FAKATRTRLRISFEPNHEPVALKRG

Download         Length: 318 bp

>AT136001 NZ_CP042596:c3924049-3923732 [Granulicella sp. WH15]
ATGAAGCGTAAATTTATACCGGCTGAAGAGTCCTTCGCACAGTGGAAGAAAGATCCGAAGTACGTCGCTGAATATGCTGC
GTTAGAGGAGGAGTTTGCACTTGCGTCCGCATTGATCGAGGCCAGGGGAAATGCCGACATGACACAGGAAGAGGTTGCGG
AGGCGATGGGAACGACGCAGGCCGTCGTTGCGCGGCTTGAGAGCGGCAAAGTCTTGCCCTCTACGCGCACGCTGGAGCGC
TTTGCGAAAGCGACCCGCACTCGACTTCGTATCAGCTTTGAACCCAATCACGAGCCTGTTGCATTGAAGCGGGGATAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References