Detailed information of TA system TA135733

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): prlF-yhaV (relBE)/YhaV-PrlF
• Location: 2361913..2362742
• Replicon: chromosome
• Accession: NZ_CP042499
• Organism: Enterobacter sp. E76

Toxin (Protein)

• Gene name: yhaV
• Uniprot ID: -
• Locus tag: FR762_RS11310
• Protein ID: WP_151603749.1
• Coordinates: 2362260..2362742 (+)
• Length: 161 a.a.

Antitoxin (Protein)

• Gene name: prlF
• Uniprot ID: -
• Locus tag: FR762_RS11305
• Protein ID: WP_125295554.1
• Coordinates: 2361913..2362257 (+)
• Length: 115 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin endonuclease, YhaV (12-147)

Antitoxin

• PrlF antitoxin (15-113)

Sequences

Toxin

Protein

• Length: 161 a.a.
• Molecular weight: 18498.27 Da
• Isoelectric Point: 10.1532

>T135733 WP_151603749.1 NZ_CP042499:2362260-2362742 [Enterobacter sp. E76]
MNGMRAVGPWKVYQHPCFVAQVKALRDEVAALKHHYPDDYRNKAATRLLAAINNARKDISADPTQAKFRLGDTLGAGYRH
WFRAKFLGQYRLFFRYSLRERIIILAWVNDSQTKRAYGNKRDAYKVFGEMLASGYPPDDWEALLKETMKQVSLSLCEPQP

Nucleotide

• Length: 483 bp

>T135733 NZ_CP042499:2362260-2362742 [Enterobacter sp. E76]
ATGAATGGAATGCGGGCAGTGGGCCCATGGAAAGTGTATCAACACCCCTGTTTTGTTGCCCAGGTTAAGGCGCTTCGGGA
CGAGGTAGCCGCGCTCAAACATCACTATCCTGACGACTACCGAAACAAAGCGGCAACCAGGCTGTTAGCGGCTATCAACA
ACGCCCGCAAAGATATCTCTGCTGACCCAACCCAGGCAAAATTTCGCCTGGGTGACACGTTGGGCGCGGGTTACAGGCAC
TGGTTTCGGGCAAAGTTTCTCGGCCAGTATCGCTTATTTTTTCGCTATAGCCTGAGAGAACGCATCATTATTCTCGCATG
GGTCAATGATTCGCAAACGAAGCGCGCTTATGGCAATAAGCGAGATGCGTATAAGGTTTTCGGTGAAATGCTGGCTTCAG
GGTATCCACCGGATGACTGGGAAGCCTTACTCAAAGAGACGATGAAGCAAGTCAGCCTGAGTCTGTGCGAACCTCAACCC
TGA

Antitoxin

Protein

• Length: 115 a.a.
• Molecular weight: 12402.85 Da
• Isoelectric Point: 3.9590

>AT135733 WP_125295554.1 NZ_CP042499:2361913-2362257 [Enterobacter sp. E76]
MNNVVMAGVTLRASSKLTARSQTTIPASVRDAMNLKPGEEIEYAVLADGQVLMTRKQTDAEDDPVMEGFLSFLANDIQHN
PSQIHALDTAFWDDVEALTEGVDVDLDAPLADEK

Nucleotide

• Length: 345 bp

>AT135733 NZ_CP042499:2361913-2362257 [Enterobacter sp. E76]
ATGAATAACGTAGTCATGGCAGGCGTAACGCTGCGAGCTTCCTCGAAATTAACTGCCCGTAGCCAGACAACCATTCCGGC
TTCTGTTAGAGATGCTATGAATTTAAAACCTGGCGAAGAGATTGAATATGCCGTCCTGGCTGACGGGCAGGTGCTGATGA
CGCGAAAGCAAACGGATGCCGAAGACGATCCGGTTATGGAAGGTTTTCTGAGCTTCCTTGCTAACGATATTCAGCACAAT
CCGTCGCAGATCCACGCGCTGGATACGGCGTTCTGGGATGACGTAGAGGCATTAACAGAAGGTGTGGATGTCGATCTCGA
TGCGCCGCTTGCTGATGAGAAATGA