Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 3195610..3196225 Replicon chromosome
Accession NZ_CP042382
Organism Pistricoccus aurantiacus strain CBA4606

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag FGL86_RS15110 Protein ID WP_147186231.1
Coordinates 3195902..3196225 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag FGL86_RS15105 Protein ID WP_147185467.1
Coordinates 3195610..3195909 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FGL86_RS15080 3191607..3192335 - 729 WP_186764419.1 PilZ domain-containing protein -
FGL86_RS15085 3192903..3194099 + 1197 WP_147185459.1 FliC/FljB family flagellin -
FGL86_RS15090 3194192..3194851 + 660 WP_147185461.1 hypothetical protein -
FGL86_RS15095 3195048..3195272 + 225 WP_147185463.1 hypothetical protein -
FGL86_RS15100 3195294..3195569 - 276 WP_147185465.1 helix-turn-helix domain-containing protein -
FGL86_RS15105 3195610..3195909 - 300 WP_147185467.1 helix-turn-helix domain-containing protein Antitoxin
FGL86_RS15110 3195902..3196225 - 324 WP_147186231.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FGL86_RS15115 3196268..3196465 - 198 WP_147185469.1 transposase -
FGL86_RS15120 3196465..3196857 - 393 WP_147185471.1 type II toxin-antitoxin system VapC family toxin -
FGL86_RS15125 3196930..3197421 - 492 WP_147186232.1 pilin -
FGL86_RS15130 3197657..3199411 + 1755 WP_147185472.1 type IV-A pilus assembly ATPase PilB -
FGL86_RS15135 3199534..3200763 + 1230 WP_147185474.1 type II secretion system F family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(32-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(38-91)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11937.93 Da        Isoelectric Point: 8.4538

>T135644 WP_147186231.1 NZ_CP042382:c3196225-3195902 [Pistricoccus aurantiacus]
MVFIELPIFIRCANALFTDADLTELQITLLENPAAGDLIPGGKGLRKIRAPLPGRGKRGGARVIYYYWVSKEKCYLVYAY
AKNVAADLTKDQLHRLAAVIEAEVRDE

Download         Length: 324 bp

>T135644 NZ_CP042382:c3196225-3195902 [Pistricoccus aurantiacus]
ATGGTCTTCATCGAACTGCCCATTTTTATTCGCTGCGCTAATGCACTATTTACAGATGCAGATTTGACCGAGCTTCAAAT
TACGTTGCTCGAGAATCCAGCAGCAGGCGATCTTATTCCTGGCGGCAAGGGATTGCGCAAAATACGCGCTCCTTTACCGG
GGCGAGGAAAACGAGGTGGCGCTCGAGTCATTTATTATTATTGGGTATCGAAAGAGAAATGCTATCTCGTATATGCCTAT
GCCAAGAATGTGGCAGCAGACTTGACGAAAGATCAATTACACCGTTTGGCTGCCGTCATTGAAGCGGAGGTGCGAGATGA
ATGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11373.09 Da        Isoelectric Point: 9.9177

>AT135644 WP_147185467.1 NZ_CP042382:c3195909-3195610 [Pistricoccus aurantiacus]
MNEQSFDELLESVRDMGHHMRGELVQGVRTREFPEPDVKAIRERTGLSQTRFAYLIGVKPKTLQNWEQKRVRPTGPARAL
LKIIEVNPDALAAIHVREV

Download         Length: 300 bp

>AT135644 NZ_CP042382:c3195909-3195610 [Pistricoccus aurantiacus]
ATGAATGAACAGTCTTTTGACGAACTGCTGGAAAGCGTTCGAGATATGGGTCATCACATGCGTGGTGAACTGGTGCAGGG
AGTTCGGACTCGAGAATTTCCTGAACCAGACGTGAAAGCTATCCGCGAGCGTACCGGCTTATCACAGACTCGATTCGCCT
ATTTAATAGGCGTGAAACCGAAGACGCTCCAGAACTGGGAACAGAAGCGGGTTCGTCCAACGGGTCCTGCGCGAGCACTG
CTGAAAATCATTGAGGTAAATCCGGACGCTTTGGCTGCGATTCATGTCCGAGAGGTGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References