Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
Location | 887394..888025 | Replicon | chromosome |
Accession | NZ_CP042382 | ||
Organism | Pistricoccus aurantiacus strain CBA4606 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | FGL86_RS04240 | Protein ID | WP_147183427.1 |
Coordinates | 887394..887687 (+) | Length | 98 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | FGL86_RS04245 | Protein ID | WP_147183428.1 |
Coordinates | 887702..888025 (+) | Length | 108 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FGL86_RS04220 | 883550..884152 | + | 603 | WP_147183423.1 | RdgB/HAM1 family non-canonical purine NTP pyrophosphatase | - |
FGL86_RS04225 | 884149..885318 | + | 1170 | WP_147183424.1 | radical SAM family heme chaperone HemW | - |
FGL86_RS04230 | 885430..886113 | + | 684 | WP_147183425.1 | OmpA family protein | - |
FGL86_RS04235 | 886192..887040 | + | 849 | WP_147183426.1 | 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ | - |
FGL86_RS04240 | 887394..887687 | + | 294 | WP_147183427.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
FGL86_RS04245 | 887702..888025 | + | 324 | WP_147183428.1 | HigA family addiction module antidote protein | Antitoxin |
FGL86_RS04250 | 888226..889590 | - | 1365 | WP_147183429.1 | tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE | - |
FGL86_RS04255 | 889681..891384 | - | 1704 | WP_147183430.1 | membrane protein insertase YidC | - |
FGL86_RS04260 | 891498..891875 | - | 378 | WP_147183431.1 | ribonuclease P protein component | - |
FGL86_RS04265 | 891889..892023 | - | 135 | WP_147183432.1 | 50S ribosomal protein L34 | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 11414.85 Da Isoelectric Point: 6.2186
>T135639 WP_147183427.1 NZ_CP042382:887394-887687 [Pistricoccus aurantiacus]
MAVEFRDAWLDAFYEQDQSHKKVPSTIEGALFRKIQILDAATQESDLRIPPGNRFEHLQGNLWGWCSIRVNKQYRLIFRW
EDSTALDTYLDPHAYKG
MAVEFRDAWLDAFYEQDQSHKKVPSTIEGALFRKIQILDAATQESDLRIPPGNRFEHLQGNLWGWCSIRVNKQYRLIFRW
EDSTALDTYLDPHAYKG
Download Length: 294 bp
>T135639 NZ_CP042382:887394-887687 [Pistricoccus aurantiacus]
ATGGCGGTTGAGTTCAGGGATGCGTGGCTGGATGCTTTCTATGAGCAAGACCAGAGCCATAAGAAAGTACCCAGCACCAT
TGAAGGTGCCCTTTTCAGGAAGATTCAGATTCTCGATGCCGCGACGCAGGAGTCAGACTTAAGGATTCCGCCGGGTAACC
GGTTTGAACATTTGCAGGGAAACCTGTGGGGCTGGTGTTCCATCCGGGTAAACAAACAGTATCGCCTGATCTTTCGCTGG
GAAGACAGCACCGCCCTGGATACGTACCTGGACCCGCACGCGTACAAGGGTTAG
ATGGCGGTTGAGTTCAGGGATGCGTGGCTGGATGCTTTCTATGAGCAAGACCAGAGCCATAAGAAAGTACCCAGCACCAT
TGAAGGTGCCCTTTTCAGGAAGATTCAGATTCTCGATGCCGCGACGCAGGAGTCAGACTTAAGGATTCCGCCGGGTAACC
GGTTTGAACATTTGCAGGGAAACCTGTGGGGCTGGTGTTCCATCCGGGTAAACAAACAGTATCGCCTGATCTTTCGCTGG
GAAGACAGCACCGCCCTGGATACGTACCTGGACCCGCACGCGTACAAGGGTTAG
Antitoxin
Download Length: 108 a.a. Molecular weight: 12190.21 Da Isoelectric Point: 9.8626
>AT135639 WP_147183428.1 NZ_CP042382:887702-888025 [Pistricoccus aurantiacus]
MRTTKRRPVTVGQMLVTEFLEPMNIEISELAEAMGVHRNTLSRIVHDKGTLTAPMAIKLAAALGNTPEFWLNIQHAVELW
DVRHRAYEQEAKNVKRVKPHVLPLEQA
MRTTKRRPVTVGQMLVTEFLEPMNIEISELAEAMGVHRNTLSRIVHDKGTLTAPMAIKLAAALGNTPEFWLNIQHAVELW
DVRHRAYEQEAKNVKRVKPHVLPLEQA
Download Length: 324 bp
>AT135639 NZ_CP042382:887702-888025 [Pistricoccus aurantiacus]
ATGAGAACTACAAAGCGTCGTCCGGTGACCGTGGGCCAAATGCTGGTCACCGAGTTCCTGGAGCCGATGAATATTGAAAT
CAGTGAGCTGGCTGAAGCCATGGGTGTGCACAGAAATACCCTCAGTCGGATTGTTCATGACAAAGGCACCTTGACCGCGC
CCATGGCCATCAAGCTGGCAGCGGCTCTGGGAAATACACCGGAGTTCTGGCTGAACATTCAGCACGCGGTTGAGTTATGG
GATGTTCGTCATCGTGCCTATGAACAAGAAGCCAAGAATGTGAAGCGCGTTAAGCCCCACGTCCTGCCTCTGGAGCAAGC
CTGA
ATGAGAACTACAAAGCGTCGTCCGGTGACCGTGGGCCAAATGCTGGTCACCGAGTTCCTGGAGCCGATGAATATTGAAAT
CAGTGAGCTGGCTGAAGCCATGGGTGTGCACAGAAATACCCTCAGTCGGATTGTTCATGACAAAGGCACCTTGACCGCGC
CCATGGCCATCAAGCTGGCAGCGGCTCTGGGAAATACACCGGAGTTCTGGCTGAACATTCAGCACGCGGTTGAGTTATGG
GATGTTCGTCATCGTGCCTATGAACAAGAAGCCAAGAATGTGAAGCGCGTTAAGCCCCACGTCCTGCCTCTGGAGCAAGC
CTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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