Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 18901..19600 Replicon plasmid unnamed2
Accession NZ_CP042359
Organism Rahnella aquatilis strain H145

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag FS594_RS26110 Protein ID WP_217137596.1
Coordinates 18901..19197 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag FS594_RS26115 Protein ID WP_217137595.1
Coordinates 19199..19600 (+) Length 134 a.a.

Genomic Context

FS594_RS26070FS594_RS26075FS594_RS26080FS594_RS26085FS594_RS26090FS594_RS26095FS594_RS26100FS594_RS26105FS594_RS26110FS594_RS26115FS594_RS26120FS594_RS26125FS594_RS26130FS594_RS26135FS594_RS26140FS594_RS26145FS594_RS26155FS594_RS26150
Location: 14057..14896 (840 bp)
Type: Others
Protein ID: WP_235174826.1
Location: 15475..15657 (183 bp)
Type: Others
Protein ID: Protein_16
Location: 15999..16241 (243 bp)
Type: Others
Protein ID: WP_235174827.1
Location: 16511..16852 (342 bp)
Type: Others
Protein ID: WP_235174829.1
Location: 16849..17163 (315 bp)
Type: Others
Protein ID: WP_235174831.1
Location: 17641..17880 (240 bp)
Type: Others
Protein ID: Protein_20
Location: 17877..18125 (249 bp)
Type: Others
Protein ID: WP_217137598.1
Location: 18261..18806 (546 bp)
Type: Others
Protein ID: WP_235174833.1
Location: 18901..19197 (297 bp)
Type: Toxin
Protein ID: WP_217137596.1
Location: 19199..19600 (402 bp)
Type: Antitoxin
Protein ID: WP_217137595.1
Location: 20287..20661 (375 bp)
Type: Others
Protein ID: WP_235174835.1
Location: 20671..20898 (228 bp)
Type: Others
Protein ID: WP_112198754.1
Location: 20945..21274 (330 bp)
Type: Others
Protein ID: WP_235174837.1
Location: 21389..21634 (246 bp)
Type: Others
Protein ID: WP_235174839.1
Location: 21688..22062 (375 bp)
Type: Others
Protein ID: WP_235174841.1
Location: 22056..22916 (861 bp)
Type: Others
Protein ID: WP_235174842.1
Location: 23631..23870 (240 bp)
Type: Others
Protein ID: WP_235174844.1
Location: 23106..23348 (243 bp)
Type: Others
Protein ID: WP_235174843.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
FS594_RS26070 (FS594_26245)14057..14896+840WP_235174826.1VOC family protein-
FS594_RS26075 (FS594_26255)15475..15657+183Protein_16DUF905 family protein-
FS594_RS26080 (FS594_26260)15999..16241+243WP_235174827.1hypothetical protein-
FS594_RS26085 (FS594_26265)16511..16852+342WP_235174829.1type II toxin-antitoxin system RelE/ParE family toxin-
FS594_RS26090 (FS594_26270)16849..17163+315WP_235174831.1type II toxin-antitoxin system MqsA family antitoxin-
FS594_RS26095 (FS594_26280)17641..17880+240Protein_20LysR family transcriptional regulator-
FS594_RS26100 (FS594_26285)17877..18125+249WP_217137598.1EexN family lipoprotein-
FS594_RS26105 (FS594_26290)18261..18806+546WP_235174833.1hypothetical protein-
FS594_RS26110 (FS594_26295)18901..19197+297WP_217137596.1type II toxin-antitoxin system MqsR family toxinToxin
FS594_RS26115 (FS594_26300)19199..19600+402WP_217137595.1type II toxin-antitoxin system MqsA family antitoxinAntitoxin
FS594_RS26120 (FS594_26305)20287..20661+375WP_235174835.1hypothetical protein-
FS594_RS26125 (FS594_26310)20671..20898+228WP_112198754.1hypothetical protein-
FS594_RS26130 (FS594_26315)20945..21274+330WP_235174837.1hypothetical protein-
FS594_RS26135 (FS594_26320)21389..21634+246WP_235174839.1hypothetical protein-
FS594_RS26140 (FS594_26325)21688..22062+375WP_235174841.1DUF3085 domain-containing protein-
FS594_RS26145 (FS594_26330)22056..22916+861WP_235174842.1DUF4942 domain-containing protein-
FS594_RS26150 (FS594_26335)23106..23348-243WP_235174843.1hypothetical protein-
FS594_RS26155 (FS594_26340)23631..23870+240WP_235174844.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideConjugative plasmid-mrkH / mrkJ / mrkF / mrkD / mrkC / mrkB / mrkA1..467533467533


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Antitoxin MqsA/HigA-2

(1-130)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10763.42 Da        Isoelectric Point: 8.5042

>T135587 WP_217137596.1 NZ_CP042359:18901-19197 [Rahnella aquatilis]
MEKRTPHTRLHIVQGLVAAGKVKATNTALNGADNLGLTFDDMCSAILGLTAADFFKSMTTYNDHTVWQDVYRPKLSCGDV
YLKLTVSNGVLIVSFKEK

Download         Length: 297 bp

>T135587 NZ_CP042359:18901-19197 [Rahnella aquatilis]
ATGGAAAAGAGAACTCCACATACGCGCCTTCATATCGTTCAGGGACTTGTTGCAGCAGGGAAGGTGAAAGCCACCAATAC
GGCGCTCAACGGCGCGGATAATTTAGGGCTGACATTTGATGATATGTGTAGCGCGATCCTGGGATTAACGGCAGCTGATT
TTTTTAAAAGTATGACCACCTATAATGATCATACTGTCTGGCAGGACGTATATCGCCCGAAGTTGTCGTGTGGTGACGTA
TATCTAAAACTAACGGTCAGTAACGGTGTTTTGATCGTCTCATTCAAGGAGAAGTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14994.44 Da        Isoelectric Point: 8.1347

>AT135587 WP_217137595.1 NZ_CP042359:19199-19600 [Rahnella aquatilis]
MKCSVCGGAELEFGIKKVPYSFRGRKTVIEAEGDHCPACGEVVMDREQSMAYMEKVKSFKAKIIAETIEPEYIIQVRKKL
ELTQKEASEIFGGGVNAFSRYEKGKAQPHPSIIKLLRVLDHHPELLDEVRKQA

Download         Length: 402 bp

>AT135587 NZ_CP042359:19199-19600 [Rahnella aquatilis]
ATGAAATGTTCCGTTTGTGGCGGTGCAGAACTTGAGTTTGGTATCAAAAAAGTCCCTTACTCATTCCGTGGCCGTAAAAC
AGTTATCGAGGCAGAAGGTGACCACTGTCCGGCGTGTGGTGAAGTCGTGATGGATCGTGAGCAGTCTATGGCCTACATGG
AAAAGGTGAAGTCATTTAAGGCCAAAATCATTGCGGAAACCATCGAACCTGAGTACATCATTCAGGTGCGTAAAAAACTT
GAACTCACGCAGAAAGAGGCCAGCGAGATTTTTGGCGGGGGCGTGAATGCCTTTTCGCGTTATGAAAAGGGTAAGGCACA
GCCACACCCTTCGATCATCAAACTCCTGCGCGTACTCGATCACCATCCCGAGTTATTGGATGAAGTGCGCAAACAGGCAT
AA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References