Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2224904..2225167 Replicon chromosome
Accession NZ_CP042348
Organism Staphylococcus aureus strain BSN9R

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FSN22_RS11360 Protein ID WP_001802298.1
Coordinates 2225063..2225167 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF4
Locus tag -
Coordinates 2224904..2225068 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FSN22_RS11340 2221087..2221752 - 666 WP_001024094.1 SDR family oxidoreductase -
FSN22_RS11345 2221904..2222224 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FSN22_RS11350 2222226..2223206 + 981 WP_000019744.1 CDF family zinc efflux transporter CzrB -
FSN22_RS11355 2223472..2224563 + 1092 WP_000495671.1 lytic regulatory protein -
- 2224904..2225068 + 165 - - Antitoxin
FSN22_RS11360 2225063..2225167 - 105 WP_001802298.1 hypothetical protein Toxin
FSN22_RS11365 2225328..2225811 - 484 Protein_2139 recombinase family protein -
FSN22_RS11370 2225854..2226990 - 1137 WP_000115564.1 SAP domain-containing protein -
FSN22_RS11375 2227279..2227371 + 93 WP_001790138.1 hypothetical protein -
FSN22_RS11380 2228076..2228933 - 858 WP_000370924.1 Cof-type HAD-IIB family hydrolase -
FSN22_RS11385 2229001..2229783 - 783 WP_000908176.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T135481 WP_001802298.1 NZ_CP042348:c2225167-2225063 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T135481 NZ_CP042348:c2225167-2225063 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTTATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 165 bp

>AT135481 NZ_CP042348:2224904-2225068 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCATTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAAATGCCGGTCAAAGCGAATAGAAGGT
TATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References