Detailed information of TA system TA135472

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1889294..1889476
• Replicon: chromosome
• Accession: NZ_CP042348
• Organism: Staphylococcus aureus strain BSN9R

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: FSN22_RS09310
• Protein ID: WP_001801861.1
• Coordinates: 1889294..1889389 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1889417..1889476 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FSN22_RS09260	1884954..1885580	+	627	Protein_1778	hypothetical protein	-
FSN22_RS09265	1885621..1885965	+	345	WP_000627551.1	DUF3969 family protein	-
FSN22_RS09270	1886063..1886614	+	552	WP_000414205.1	hypothetical protein	-
FSN22_RS09275	1886832..1887473	-	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
FSN22_RS09280	1887587..1887772	-	186	WP_000809857.1	hypothetical protein	-
FSN22_RS09285	1887774..1887950	-	177	WP_000375476.1	hypothetical protein	-
FSN22_RS09290	1887961..1888344	-	384	WP_000070811.1	hypothetical protein	-
FSN22_RS09300	1888948..1889091	-	144	WP_001549059.1	transposase	-
FSN22_RS09310	1889294..1889389	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1889417..1889476	-	60	-	-	Antitoxin
FSN22_RS09315	1889512..1889613	+	102	WP_001791893.1	hypothetical protein	-
FSN22_RS09320	1889591..1889767	-	177	Protein_1788	transposase	-
FSN22_RS09325	1889961..1890338	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1882394..1907996	25602

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T135472 WP_001801861.1 NZ_CP042348:1889294-1889389 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T135472 NZ_CP042348:1889294-1889389 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT135472 NZ_CP042348:c1889476-1889417 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin