135443

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 1044774..1044936 Replicon chromosome
Accession NZ_CP042341
Organism Staphylococcus capitis strain BN2

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A7Z7YYS1
Locus tag FRG19_RS05025 Protein ID WP_049428026.1
Coordinates 1044774..1044878 (+) Length 35 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 1044906..1044936 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FRG19_RS05015 1040706..1043645 + 2940 WP_194251442.1 AAA family ATPase -
FRG19_RS05020 1043642..1044583 + 942 WP_049428024.1 3'-5' exoribonuclease YhaM -
FRG19_RS05025 1044774..1044878 + 105 WP_049428026.1 type I toxin-antitoxin system Fst family toxin Toxin
- 1044906..1044936 + 31 - - Antitoxin
FRG19_RS05030 1045033..1046034 - 1002 WP_194251443.1 peptidylprolyl isomerase -
FRG19_RS05035 1046236..1046805 - 570 WP_193626992.1 DUF3267 domain-containing protein -
FRG19_RS05040 1046997..1047368 - 372 WP_049428031.1 YtxH domain-containing protein -
FRG19_RS05045 1047446..1047871 - 426 WP_049428034.1 HIT family protein -
FRG19_RS05050 1048004..1048744 + 741 WP_002453567.1 ABC transporter ATP-binding protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 3894.63 Da        Isoelectric Point: 9.5124

>T135443 WP_049428026.1 NZ_CP042341:1044774-1044878 [Staphylococcus capitis]
MLFDIFVHIMATATSGCIVALFAHWLSTRNDKRK

Download         Length: 105 bp

>T135443 NZ_CP042341:1044774-1044878 [Staphylococcus capitis]
ATGTTATTTGATATCTTTGTACACATCATGGCCACGGCAACCAGTGGTTGTATCGTTGCTTTATTCGCGCATTGGCTAAG
CACTCGCAACGATAAACGTAAATAG

Antitoxin


Download         Length: 31 bp

>AT135443 NZ_CP042341:1044906-1044936 [Staphylococcus capitis]
AAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A7Z7YYS1


Antitoxin

Download structure file

References