Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_37
Location 60075..60673 Replicon chromosome
Accession NZ_CP042304
Organism Devosia ginsengisoli strain Gsoil 520

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag FPZ08_RS00325 Protein ID WP_146288144.1
Coordinates 60075..60398 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag FPZ08_RS00330 Protein ID WP_186767303.1
Coordinates 60428..60673 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPZ08_RS00310 55760..56806 - 1047 WP_146288142.1 extracellular solute-binding protein -
FPZ08_RS00315 57005..59530 - 2526 WP_146288143.1 hypothetical protein -
FPZ08_RS00325 60075..60398 + 324 WP_146288144.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FPZ08_RS00330 60428..60673 + 246 WP_186767303.1 helix-turn-helix domain-containing protein Antitoxin
FPZ08_RS00335 60670..60897 + 228 WP_146288146.1 hypothetical protein -
FPZ08_RS00340 60986..62764 - 1779 WP_146288147.1 pilus assembly protein -
FPZ08_RS00345 62830..63453 - 624 WP_146288148.1 L,D-transpeptidase -
FPZ08_RS00350 63597..63992 - 396 WP_186767144.1 response regulator -
FPZ08_RS00355 64169..64792 + 624 WP_146288150.1 DNA-3-methyladenine glycosylase I -
FPZ08_RS00360 65130..65390 + 261 WP_146288151.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(14-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(26-71)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12253.58 Da        Isoelectric Point: 10.3951

>T135213 WP_146288144.1 NZ_CP042304:60075-60398 [Devosia ginsengisoli]
MKWTVETLDVADAEIEALPPALQARLLRLMEMVEMVGLEQLREPHVKHIDGKLWELRAKATEGIARGLYVTMTGRRVVIL
HVFVKKSRKTPRNALDIALERMKQVTP

Download         Length: 324 bp

>T135213 NZ_CP042304:60075-60398 [Devosia ginsengisoli]
ATGAAATGGACGGTTGAAACCCTCGATGTAGCCGATGCTGAAATCGAGGCATTGCCGCCCGCACTGCAGGCCCGGCTTCT
CCGCCTCATGGAAATGGTGGAGATGGTCGGTCTGGAGCAATTGCGCGAGCCCCACGTCAAGCACATCGACGGCAAGTTGT
GGGAGTTGCGTGCCAAGGCGACGGAAGGGATTGCGCGCGGTCTCTATGTGACGATGACCGGGCGCCGCGTGGTCATCCTC
CACGTGTTCGTCAAGAAGTCCCGGAAGACGCCGCGCAATGCTCTGGATATTGCCCTGGAACGAATGAAGCAGGTGACGCC
GTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8729.95 Da        Isoelectric Point: 7.0117

>AT135213 WP_186767303.1 NZ_CP042304:60428-60673 [Devosia ginsengisoli]
MDNPEFKAEYEKADAEFALVEALVLARTKAKLSQAELAKRIGTTQSAIARLEGGGVSPSLSTLKRYADATGSRLHIELVP
Q

Download         Length: 246 bp

>AT135213 NZ_CP042304:60428-60673 [Devosia ginsengisoli]
ATGGACAATCCGGAGTTCAAGGCCGAATACGAGAAGGCCGATGCTGAGTTTGCACTTGTCGAAGCTCTGGTTCTGGCTCG
CACCAAGGCCAAGCTCTCTCAGGCCGAATTGGCCAAGCGGATTGGCACCACCCAATCGGCCATAGCCCGGCTTGAAGGGG
GTGGCGTATCACCCTCGCTGTCCACTCTGAAACGCTATGCCGATGCCACCGGCTCGCGCTTGCATATTGAGCTTGTGCCG
CAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References