Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 2639732..2640255 Replicon chromosome
Accession NZ_CP042286
Organism Staphylococcus argenteus strain B3-25B

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag FPV14_RS12750 Protein ID WP_047431394.1
Coordinates 2639732..2639998 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag FPV14_RS12755 Protein ID WP_047431397.1
Coordinates 2639998..2640255 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPV14_RS12730 2635094..2636281 - 1188 WP_031787204.1 MFS transporter -
FPV14_RS12735 2636625..2637398 - 774 WP_000072156.1 iron export ABC transporter permease subunit FetB -
FPV14_RS12740 2637391..2638053 - 663 WP_000923518.1 ATP-binding cassette domain-containing protein -
FPV14_RS12745 2638301..2639377 - 1077 WP_047431390.1 M42 family metallopeptidase -
FPV14_RS12750 2639732..2639998 - 267 WP_047431394.1 Txe/YoeB family addiction module toxin Toxin
FPV14_RS12755 2639998..2640255 - 258 WP_047431397.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
FPV14_RS12760 2640612..2641076 + 465 WP_000736690.1 DUF1307 domain-containing protein -
FPV14_RS12765 2641244..2642821 - 1578 WP_047556123.1 FMN-binding glutamate synthase family protein -
FPV14_RS12770 2643015..2643764 + 750 WP_047556121.1 hypothetical protein -
FPV14_RS12775 2643991..2645184 - 1194 WP_000675397.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(24-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10625.19 Da        Isoelectric Point: 10.1383

>T135153 WP_047431394.1 NZ_CP042286:c2639998-2639732 [Staphylococcus argenteus]
MSNYTVKIKNSAKSDLKKIKNSYLKKSFLEIVETLKNDPYKITQSFEKLEPKYLERYSRRINHQHRVVYTVDDRNKEVLI
LSAWSHYD

Download         Length: 267 bp

>T135153 NZ_CP042286:c2639998-2639732 [Staphylococcus argenteus]
ATGAGCAATTACACGGTTAAGATTAAAAATTCGGCGAAATCAGATTTAAAGAAAATAAAAAATTCTTATTTAAAGAAGTC
ATTTTTAGAAATTGTTGAAACATTAAAAAATGATCCGTATAAAATAACACAATCCTTTGAAAAATTAGAACCTAAATATT
TAGAGCGATATTCAAGAAGAATTAACCATCAGCACAGGGTAGTCTATACCGTAGATGATCGAAATAAAGAAGTATTAATA
CTATCGGCGTGGTCACATTATGATTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9760.71 Da        Isoelectric Point: 4.1232

>AT135153 WP_047431397.1 NZ_CP042286:c2640255-2639998 [Staphylococcus argenteus]
MIITSPTEARKDFYQLLKNVNNNHEPIYISGNNAENNAVIIGLDDWKSIQETIYLESTGTMDKVREREKDNSGTTNIDDI
DWDNL

Download         Length: 258 bp

>AT135153 NZ_CP042286:c2640255-2639998 [Staphylococcus argenteus]
ATGATTATCACTAGCCCTACAGAAGCGAGAAAAGATTTTTATCAATTACTAAAAAATGTTAATAATAATCACGAGCCAAT
TTATATTAGTGGCAATAATGCCGAAAATAATGCTGTGATTATAGGTTTAGATGATTGGAAAAGTATACAAGAAACAATAT
ATCTGGAATCTACTGGTACAATGGATAAAGTAAGAGAAAGAGAAAAAGATAATAGTGGTACAACAAATATAGATGATATT
GATTGGGATAATCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References