Detailed information of TA system TA135146

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 2054601..2054781
• Replicon: chromosome
• Accession: NZ_CP042286
• Organism: Staphylococcus argenteus strain B3-25B

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: FPV14_RS09685
• Protein ID: WP_001801861.1
• Coordinates: 2054601..2054696 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	2054724..2054781 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FPV14_RS09645	2049661..2050656	+	996	WP_072467221.1	DUF4352 domain-containing protein	-
FPV14_RS09650	2050732..2051358	+	627	WP_047556358.1	hypothetical protein	-
FPV14_RS09655	2051399..2051740	+	342	WP_047556357.1	DUF3969 family protein	-
FPV14_RS09660	2051841..2052413	+	573	WP_047556356.1	hypothetical protein	-
FPV14_RS09665	2052610..2053167	-	558	WP_047556355.1	ImmA/IrrE family metallo-endopeptidase	-
FPV14_RS09670	2053352..2053798	-	447	WP_031787841.1	DUF1433 domain-containing protein	-
FPV14_RS09675	2053920..2054178	-	259	Protein_1872	IS3 family transposase	-
FPV14_RS09680	2054220..2054456	-	237	WP_047556353.1	IS3 family transposase	-
FPV14_RS09685	2054601..2054696	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	2054724..2054781	-	58	-	-	Antitoxin
FPV14_RS09695	2055707..2056150	-	444	WP_047556351.1	DUF1433 domain-containing protein	-
FPV14_RS09700	2056150..2056592	-	443	Protein_1876	DUF1433 domain-containing protein	-
FPV14_RS09705	2056592..2057038	-	447	WP_047556344.1	DUF1433 domain-containing protein	-
FPV14_RS09710	2057038..2057481	-	444	WP_047556340.1	DUF1433 domain-containing protein	-
FPV14_RS09715	2057481..2057924	-	444	WP_047556338.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2054220..2054456	236

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T135146 WP_001801861.1 NZ_CP042286:2054601-2054696 [Staphylococcus argenteus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T135146 NZ_CP042286:2054601-2054696 [Staphylococcus argenteus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin

Nucleotide

• Length: 58 bp

>AT135146 NZ_CP042286:c2054781-2054724 [Staphylococcus argenteus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin