134967

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 1906440..1907140 Replicon chromosome
Accession NZ_CP042180
Organism Pseudomonas sp. KBS0802

Toxin (Protein)


Gene name mqsR Uniprot ID Q88F93
Locus tag FFH79_RS08910 Protein ID WP_010954960.1
Coordinates 1906440..1906736 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID I7AUJ7
Locus tag FFH79_RS08915 Protein ID WP_003254235.1
Coordinates 1906739..1907140 (+) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FFH79_RS08890 1902432..1903610 - 1179 WP_010954964.1 efflux RND transporter periplasmic adaptor subunit -
FFH79_RS08895 1903823..1904299 + 477 WP_010954963.1 sigma-70 family RNA polymerase sigma factor -
FFH79_RS08900 1904468..1904947 + 480 WP_010954962.1 hypothetical protein -
FFH79_RS08905 1905020..1906345 + 1326 WP_010954961.1 MFS transporter -
FFH79_RS08910 1906440..1906736 + 297 WP_010954960.1 type II toxin-antitoxin system MqsR family toxin Toxin
FFH79_RS08915 1906739..1907140 + 402 WP_003254235.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
FFH79_RS08920 1907212..1908894 - 1683 WP_010954959.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
FFH79_RS08925 1909430..1910179 + 750 WP_003254232.1 electron transfer flavoprotein subunit beta/FixA family protein -
FFH79_RS08930 1910180..1911109 + 930 WP_010954958.1 FAD-binding protein -
FFH79_RS08935 1911185..1912006 + 822 WP_010954957.1 transporter substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(6-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-109)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11133.22 Da        Isoelectric Point: 10.2271

>T134967 WP_010954960.1 NZ_CP042180:1906440-1906736 [Pseudomonas sp. KBS0802]
MEKRMPHCPLERVKALAAARRIRPTGAALKGAKALGMDFPGMLEVITSLKRTDFYKSMTSHIDHRVWQDVYRPLTAIGYV
YLKLSVVDDVLIVSFKEL

Download         Length: 297 bp

>T134967 NZ_CP042180:1906440-1906736 [Pseudomonas sp. KBS0802]
ATGGAAAAGAGAATGCCTCATTGCCCGCTGGAGCGGGTAAAAGCCCTGGCTGCGGCAAGGCGAATCCGCCCTACGGGTGC
TGCATTGAAAGGCGCCAAGGCGCTGGGAATGGATTTTCCGGGCATGCTTGAGGTGATCACCAGCTTGAAGCGCACTGATT
TCTACAAGAGCATGACCAGCCATATTGACCACCGGGTTTGGCAGGATGTGTATCGCCCGCTTACAGCAATTGGGTACGTT
TATTTGAAATTGTCCGTGGTAGACGACGTGCTCATCGTGTCTTTCAAGGAGTTGTAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14684.76 Da        Isoelectric Point: 4.9531

>AT134967 WP_003254235.1 NZ_CP042180:1906739-1907140 [Pseudomonas sp. KBS0802]
MRCPICGGSELAPDIQGMPYSYKGEMTVIPEVSGDYCSACGECVLSHDEAMRVSHLMTAFERQVNANVVDPSFIASIRRK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALVKLLKLLDRHPELFEEVRTA

Download         Length: 402 bp

>AT134967 NZ_CP042180:1906739-1907140 [Pseudomonas sp. KBS0802]
ATGAGATGTCCAATATGCGGCGGCTCGGAGCTTGCACCTGACATTCAGGGCATGCCCTATAGCTACAAAGGCGAGATGAC
AGTGATTCCTGAGGTAAGTGGCGATTACTGCTCCGCATGTGGTGAATGTGTACTGAGTCATGATGAAGCCATGCGCGTCA
GTCACTTGATGACGGCATTCGAGCGCCAGGTCAACGCAAATGTTGTGGATCCTTCCTTTATTGCCTCCATACGCAGAAAG
TTCGACCTCGACCAGCGTGAAGCGGGGGAAATCTTCGGTGGTGGGGTCAATGCGTTCTCCCGTTATGAAAACGGCAAGAC
CACCCCGCCAGTGGCGTTGGTGAAACTGCTCAAGCTGCTGGATCGCCATCCAGAACTCTTTGAGGAAGTGCGTACTGCCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q88F93

Antitoxin

Source ID Structure
AlphaFold DB I7AUJ7

References