134966

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HTH(antitoxin)
Location 1365718..1366319 Replicon chromosome
Accession NZ_CP042180
Organism Pseudomonas sp. KBS0802

Toxin (Protein)


Gene name higB Uniprot ID A0A2L1IAQ2
Locus tag FFH79_RS06360 Protein ID WP_049587984.1
Coordinates 1366005..1366319 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A2L1IAR7
Locus tag FFH79_RS06355 Protein ID WP_049587986.1
Coordinates 1365718..1366005 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FFH79_RS06335 1360741..1361586 + 846 WP_003254799.1 hypothetical protein -
FFH79_RS06340 1361583..1363310 + 1728 WP_138868008.1 hypothetical protein -
FFH79_RS06345 1363365..1364114 + 750 WP_049587988.1 hypothetical protein -
FFH79_RS06350 1364186..1365517 - 1332 WP_004576169.1 30S ribosomal protein S12 methylthiotransferase RimO -
FFH79_RS06355 1365718..1366005 - 288 WP_049587986.1 helix-turn-helix domain-containing protein Antitoxin
FFH79_RS06360 1366005..1366319 - 315 WP_049587984.1 hypothetical protein Toxin
FFH79_RS06365 1366768..1368678 + 1911 WP_010952353.1 potassium transporter Kup -
FFH79_RS06370 1368727..1370019 - 1293 WP_010952354.1 virulence factor family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(36-88)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11784.61 Da        Isoelectric Point: 9.9097

>T134966 WP_049587984.1 NZ_CP042180:c1366319-1366005 [Pseudomonas sp. KBS0802]
MIFIETPVFTSDLKEHLDDEEYRALQAYLAEHPEAGSLLEETGGLRKIRWAAKGKGKSGGVRVIYYHVTAAHQIRMILIY
RKGIVDTLTSSQKAQLRALNKGWK

Download         Length: 315 bp

>T134966 NZ_CP042180:c1366319-1366005 [Pseudomonas sp. KBS0802]
ATGATCTTCATCGAGACCCCAGTATTCACCTCCGATCTCAAGGAGCACCTGGATGATGAAGAATACCGGGCTTTGCAGGC
CTATCTGGCCGAGCATCCCGAAGCCGGTTCTCTCCTGGAGGAAACCGGCGGCCTCAGAAAGATCCGCTGGGCAGCCAAGG
GCAAGGGCAAGAGTGGGGGTGTACGAGTGATCTACTACCACGTCACTGCAGCCCACCAGATCCGTATGATTCTGATCTAT
CGCAAGGGCATCGTGGATACCTTGACAAGCAGTCAGAAAGCGCAGCTTCGCGCACTAAACAAAGGGTGGAAATAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10841.31 Da        Isoelectric Point: 7.4063

>AT134966 WP_049587986.1 NZ_CP042180:c1366005-1365718 [Pseudomonas sp. KBS0802]
MEKHLFDRLVESMTQMDEIDRGERQPSREFHVDALQVKKIRQATGLSQAAFAKRIDVAVGTLRNWEQGRREPEGPARALL
RAIHNDPEHVLAALS

Download         Length: 288 bp

>AT134966 NZ_CP042180:c1366005-1365718 [Pseudomonas sp. KBS0802]
ATGGAAAAGCATCTCTTCGATCGTCTTGTGGAAAGCATGACTCAGATGGATGAGATCGATCGCGGTGAGCGTCAGCCCTC
GCGTGAGTTCCACGTAGACGCACTTCAAGTCAAAAAGATTCGTCAAGCCACTGGCCTTTCCCAGGCTGCGTTTGCCAAAC
GTATCGATGTCGCAGTAGGAACTCTACGGAATTGGGAACAGGGCCGTCGCGAACCTGAAGGACCAGCTCGTGCCTTGCTT
CGAGCGATTCATAACGATCCCGAACATGTACTTGCGGCCTTGAGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2L1IAQ2

Antitoxin

Source ID Structure
AlphaFold DB A0A2L1IAR7

References