Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 1381097..1381768 Replicon chromosome
Accession NZ_CP042173
Organism Yersinia sp. KBS0713

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag FFE93_RS06440 Protein ID WP_049600866.1
Coordinates 1381097..1381429 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag FFE93_RS06445 Protein ID WP_138774921.1
Coordinates 1381448..1381768 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FFE93_RS06420 1376661..1377650 - 990 WP_057647346.1 aldo/keto reductase -
FFE93_RS06425 1377819..1378685 - 867 WP_049600856.1 LysR family transcriptional regulator -
FFE93_RS06430 1378787..1379269 + 483 WP_054873127.1 multidrug/biocide efflux PACE transporter -
FFE93_RS06435 1379438..1380409 + 972 WP_054873126.1 glucokinase -
FFE93_RS06440 1381097..1381429 + 333 WP_049600866.1 toxin Toxin
FFE93_RS06445 1381448..1381768 + 321 WP_138774921.1 transcriptional regulator Antitoxin
FFE93_RS06450 1381795..1383039 - 1245 WP_032898112.1 OFA family MFS transporter -
FFE93_RS06455 1383253..1383993 - 741 WP_005275421.1 LytTR family DNA-binding domain-containing protein -
FFE93_RS06460 1383997..1385697 - 1701 WP_049600872.1 sensor histidine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-88)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 12790.88 Da        Isoelectric Point: 10.4058

>T134935 WP_049600866.1 NZ_CP042173:1381097-1381429 [Yersinia sp. KBS0713]
MDAVFIELPPFERFRVGYLSDDKYRTLQITLMNNPTAGDVIQQTGGLRKMRFSDAKAGKGKRGGVRVIYYWWVERFQFLL
FAIYSKGEMSDLTNAQRKILSNLLKCRKSE

Download         Length: 333 bp

>T134935 NZ_CP042173:1381097-1381429 [Yersinia sp. KBS0713]
ATGGATGCTGTATTTATAGAACTACCGCCATTCGAGCGCTTTAGAGTGGGCTATTTATCGGATGATAAATATAGAACTTT
GCAGATTACGTTAATGAATAATCCAACTGCTGGGGATGTTATCCAACAGACCGGCGGTTTGCGCAAAATGCGATTCAGTG
ATGCAAAAGCGGGTAAAGGCAAACGTGGCGGTGTCAGAGTCATTTATTATTGGTGGGTAGAGCGTTTTCAATTTTTACTC
TTCGCCATTTATAGCAAAGGTGAGATGTCTGATTTAACCAATGCACAACGGAAAATACTTAGTAATCTTCTTAAATGCCG
TAAATCTGAATGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 12110.76 Da        Isoelectric Point: 7.4673

>AT134935 WP_138774921.1 NZ_CP042173:1381448-1381768 [Yersinia sp. KBS0713]
MEKRDLFSELVEGMGAWEEANTGKKTLKTHKVSTESSLTLTSEELRHIRETLNISQALFAHYLQAGTATYQNWEQGRAKP
NKQAILLIRMVQKDPHTLHTLAELYS

Download         Length: 321 bp

>AT134935 NZ_CP042173:1381448-1381768 [Yersinia sp. KBS0713]
ATGGAAAAAAGAGATTTATTTTCAGAGTTGGTTGAGGGAATGGGTGCATGGGAAGAGGCCAATACGGGTAAAAAAACACT
GAAAACGCACAAGGTCTCAACTGAAAGTAGCCTAACACTGACCTCTGAGGAGCTACGTCACATTCGCGAGACTTTGAATA
TTTCACAAGCGCTGTTTGCTCACTATTTACAGGCGGGAACTGCAACCTACCAGAACTGGGAGCAAGGCCGCGCTAAGCCA
AATAAGCAGGCTATTTTGCTGATTAGAATGGTACAAAAAGACCCCCATACCTTGCACACTCTGGCCGAGTTGTACTCGTG
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References