Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 566891..567591 Replicon chromosome
Accession NZ_CP042165
Organism Burkholderia contaminans strain ZCC

Toxin (Protein)


Gene name mqsR Uniprot ID A0A1E3FT75
Locus tag FPQ37_RS21240 Protein ID WP_039357707.1
Coordinates 567295..567591 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID A0A4R4BTY4
Locus tag FPQ37_RS21235 Protein ID WP_039357704.1
Coordinates 566891..567292 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FPQ37_RS21215 562546..563898 - 1353 WP_039357693.1 LLM class flavin-dependent oxidoreductase -
FPQ37_RS21220 563906..564955 - 1050 WP_039357696.1 LLM class flavin-dependent oxidoreductase -
FPQ37_RS21225 565008..565955 - 948 WP_039357698.1 ABC transporter substrate-binding protein -
FPQ37_RS21230 566012..566572 - 561 WP_039357701.1 GNAT family N-acetyltransferase -
FPQ37_RS21235 566891..567292 - 402 WP_039357704.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
FPQ37_RS21240 567295..567591 - 297 WP_039357707.1 type II toxin-antitoxin system MqsR family toxin Toxin
FPQ37_RS21245 567695..568738 - 1044 WP_039357711.1 succinylglutamate desuccinylase/aspartoacylase family protein -
FPQ37_RS21250 568990..569274 - 285 WP_039357714.1 hypothetical protein -
FPQ37_RS21255 569516..571066 - 1551 WP_039357717.1 sensor domain-containing diguanylate cyclase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Cro/C1-type helix-turn-helix domain

(72-109)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11206.04 Da        Isoelectric Point: 8.0535

>T134924 WP_039357707.1 NZ_CP042165:c567591-567295 [Burkholderia contaminans]
MEKRTPHCKLPRVKALVETGQVRLTASAVLGARLLGFTEREALDVVLSLTDLDFHKSMTTYADHTIWQDVYRPFTVRGDV
YLKLTVIDDVLIVSFKER

Download         Length: 297 bp

>T134924 NZ_CP042165:c567591-567295 [Burkholderia contaminans]
ATGGAAAAGAGAACGCCTCATTGCAAGCTGCCTCGCGTCAAGGCACTCGTCGAAACCGGCCAGGTCCGGCTAACGGCGAG
TGCGGTACTCGGCGCCCGGCTATTGGGTTTCACGGAACGGGAGGCGCTCGATGTCGTGCTGTCGCTGACCGATCTCGACT
TCCACAAGAGCATGACGACGTACGCCGACCACACGATCTGGCAGGACGTCTACCGACCTTTCACGGTGCGTGGCGACGTG
TACCTGAAACTGACGGTGATCGACGATGTGCTGATCGTGTCTTTCAAGGAGCGATGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14649.94 Da        Isoelectric Point: 8.8304

>AT134924 WP_039357704.1 NZ_CP042165:c567292-566891 [Burkholderia contaminans]
MKCPACGAARLVRDTRDIPYTYKGRSTVVRDITGDFCPACGESVLDLDEATRLGEAITEFNKQVNATIVDPKYIAKVRKK
LKLDQREAAELFGGGVNAFSRYETGKTNPPLALVKLLKLLDRHPDLLAEVRAA

Download         Length: 402 bp

>AT134924 NZ_CP042165:c567292-566891 [Burkholderia contaminans]
ATGAAGTGCCCTGCATGCGGTGCCGCCAGGCTGGTCCGCGACACGCGAGACATCCCTTATACCTACAAGGGCCGGTCGAC
TGTCGTTCGCGACATCACCGGCGATTTCTGCCCGGCCTGCGGGGAATCGGTGCTGGATCTCGACGAGGCGACCCGTCTCG
GCGAAGCGATCACCGAATTCAACAAGCAGGTGAACGCCACCATCGTCGACCCGAAGTACATCGCGAAGGTGCGCAAGAAG
CTGAAGCTGGATCAGCGCGAGGCAGCCGAGCTCTTCGGCGGTGGAGTCAACGCGTTCTCCCGTTACGAAACGGGCAAGAC
GAATCCGCCGCTTGCCCTCGTGAAATTGCTGAAGCTCCTGGATCGTCACCCCGATCTGCTCGCCGAAGTTCGAGCGGCAT
AG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1E3FT75

Antitoxin

Source ID Structure
AlphaFold DB A0A4R4BTY4

References