Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 495916..496100 Replicon chromosome
Accession NZ_CP042157
Organism Staphylococcus aureus strain B3-17D

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2U0ISP5
Locus tag FP481_RS02710 Protein ID WP_000482652.1
Coordinates 495993..496100 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 495916..495976 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FP481_RS02695 491371..491538 - 168 Protein_511 hypothetical protein -
FP481_RS02700 491769..493502 - 1734 WP_000486487.1 ABC transporter ATP-binding protein/permease -
FP481_RS02705 493527..495290 - 1764 WP_001064825.1 ABC transporter ATP-binding protein/permease -
- 495916..495976 + 61 - - Antitoxin
FP481_RS02710 495993..496100 - 108 WP_000482652.1 type I toxin-antitoxin system Fst family toxin Toxin
FP481_RS02715 496234..496620 - 387 WP_000779360.1 flippase GtxA -
FP481_RS02720 496888..498030 + 1143 WP_001176863.1 glycerate kinase -
FP481_RS02725 498090..498749 + 660 WP_000831298.1 membrane protein -
FP481_RS02730 498931..500142 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
FP481_RS02735 500265..500738 - 474 WP_000456486.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T134911 WP_000482652.1 NZ_CP042157:c496100-495993 [Staphylococcus aureus]
MFNLLINIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T134911 NZ_CP042157:c496100-495993 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 61 bp

>AT134911 NZ_CP042157:495916-495976 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2U0ISP5

Antitoxin

Download structure file

References