Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 210485..210682 Replicon chromosome
Accession NZ_CP042157
Organism Staphylococcus aureus strain B3-17D

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FP481_RS01200 Protein ID WP_001802298.1
Coordinates 210578..210682 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 210485..210523 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FP481_RS01180 206672..207337 - 666 WP_001024092.1 SDR family oxidoreductase -
FP481_RS01185 207489..207809 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FP481_RS01190 207811..208788 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
FP481_RS01195 209054..210145 + 1092 WP_000495669.1 hypothetical protein -
- 210485..210523 + 39 - - Antitoxin
FP481_RS01200 210578..210682 - 105 WP_001802298.1 hypothetical protein Toxin
FP481_RS01210 211362..211520 + 159 WP_001792784.1 hypothetical protein -
FP481_RS01220 212178..213035 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
FP481_RS01225 213103..213885 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T134909 WP_001802298.1 NZ_CP042157:c210682-210578 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T134909 NZ_CP042157:c210682-210578 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT134909 NZ_CP042157:210485-210523 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References