Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 2251397..2251594 Replicon chromosome
Accession NZ_CP042153
Organism Staphylococcus aureus strain B4-59C

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag FP482_RS11300 Protein ID WP_001802298.1
Coordinates 2251490..2251594 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 2251397..2251435 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FP482_RS11280 2247584..2248249 - 666 WP_001024092.1 SDR family oxidoreductase -
FP482_RS11285 2248401..2248721 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
FP482_RS11290 2248723..2249700 + 978 WP_000019734.1 CDF family zinc efflux transporter CzrB -
FP482_RS11295 2249966..2251057 + 1092 WP_000495669.1 hypothetical protein -
- 2251397..2251435 + 39 - - Antitoxin
FP482_RS11300 2251490..2251594 - 105 WP_001802298.1 hypothetical protein Toxin
FP482_RS11310 2252274..2252432 + 159 WP_001792784.1 hypothetical protein -
FP482_RS11320 2253090..2253947 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
FP482_RS11325 2254015..2254797 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T134897 WP_001802298.1 NZ_CP042153:c2251594-2251490 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T134897 NZ_CP042153:c2251594-2251490 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 39 bp

>AT134897 NZ_CP042153:2251397-2251435 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References