Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | sprG-sprF/- |
Location | 2779454..2779716 | Replicon | chromosome |
Accession | NZ_CP042107 | ||
Organism | Staphylococcus aureus strain B8-13D |
Toxin (Protein)
Gene name | SprG3 | Uniprot ID | Q2FWA7 |
Locus tag | FP484_RS14145 | Protein ID | WP_001802298.1 |
Coordinates | 2779612..2779716 (-) | Length | 35 a.a. |
Antitoxin (RNA)
Gene name | SprF2 | ||
Locus tag | - | ||
Coordinates | 2779454..2779617 (+) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FP484_RS14125 | 2775706..2776371 | - | 666 | WP_001024092.1 | SDR family oxidoreductase | - |
FP484_RS14130 | 2776523..2776843 | + | 321 | WP_000003759.1 | Zn(II)-responsive metalloregulatory transcriptional repressor CzrA | - |
FP484_RS14135 | 2776845..2777822 | + | 978 | WP_000019734.1 | CDF family zinc efflux transporter CzrB | - |
FP484_RS14140 | 2778088..2779179 | + | 1092 | WP_000495669.1 | hypothetical protein | - |
- | 2779454..2779617 | + | 164 | - | - | Antitoxin |
FP484_RS14145 | 2779612..2779716 | - | 105 | WP_001802298.1 | hypothetical protein | Toxin |
FP484_RS14155 | 2780396..2780554 | + | 159 | WP_001792784.1 | hypothetical protein | - |
FP484_RS14165 | 2781212..2782069 | - | 858 | WP_000370925.1 | Cof-type HAD-IIB family hydrolase | - |
FP484_RS14170 | 2782137..2782919 | - | 783 | WP_000908182.1 | ABC transporter ATP-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 35 a.a. Molecular weight: 3906.77 Da Isoelectric Point: 5.5724
>T134884 WP_001802298.1 NZ_CP042107:c2779716-2779612 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
Download Length: 105 bp
>T134884 NZ_CP042107:c2779716-2779612 [Staphylococcus aureus]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA
Antitoxin
Download Length: 164 bp
>AT134884 NZ_CP042107:2779454-2779617 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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